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TOP > Neuroimaging Facilities

Neuroimaging Facilities

Research-use 3 Tesla MRI; MRI (magnetic resonance imaging) is a technique that can get the three-dimensional information in the living body including brain with high spatial resolution of the millimeter unit by combining an electromagnetic wave with strong magnetism. MRI has been world widely used because of no radiation exposure and its non-invasiveness, relative safeness and easiness. MRI can get the detailed multidirectional information about the brain and nerve in terms of not only the structure measures but also functional measures using blood flow studies (functional MRI) or nerve tract tracing (diffusion tensor imaging). Using the research-use 3T MRI (Siemens Verio) we can simultaneously perform MRI and measurements of physiological variables including EEG, or magnetic and current stimulation by installing of 32ch head coil, soundproofing facilities, audio-visual stimulation device, and an ocular movement monitor.

 

Positron Emission Tomography; Positron emission tomography (PET) is a kind of nuclear medicine examinations for in-vivo imaging of radioactivity distribution by administration of radiopharmaceuticals labeled by positron emitter. Our nuclear medicine facility investigates pathophysiology by fusion of functional and morphological images using PET/CT (Siemens, Biograph 16) and synthetizes PET tracers labeled by short-lived radionuclides (18F, 11C, 15O, 13N) using in-house cyclotron (Sumitomo Heavy Industries, Ltd. HM-20).

 

Magnetoencephalography; Magnetoencephalography (MEG) is metering equipment evaluating a magnetic field with the electric activity of the living body. Because magnetic permeability is almost kept stable through brain, cerebrospinal fluid, bone, skin, MEG can estimate a magnetic source in the living body with high spatial and temporal resolution. MEG is mainly used for detection of the epileptic focus and the evaluation of the brain function of perception and recognition.

 

Near-infrared spectroscopy; Near-infrared spectroscopy (NIRS) is a noninvasive technique for cerebral blood flow measurements using a property that near-infrared light is absorbed to hemoglobin when passing the living body. It can measure cerebral blood flow changes within the range of 2-3 cm from the head surface. It has been clinically applied to detection of epileptic focus and determination of dominant speech area. It has been firstly accepted as an advanced medical treatment in psychiatry as "an adjunct to differential diagnosis of the depressive symptoms" from April, 2009. We investigate possibility of NIRS as a biomarker of prognosis, the treatment-responsibility, and decision of disease severity in psychiatric diseases while performing detection of epileptic focus, decision of dominant speech area, and advanced medical treatment in psychiatry.

 

Imaging facilities for animal; As heavy neuroimaging devices for animals, 3T MRI (Siemens Trio), animal PET/CT (Shimadzu Clairvivo PET), and in-house cyclotron (Sumitomo Heavy Industries, Ltd. HM-12) are used in cooperation with National Institute of Neuroscience.