2010 原著

  1. Numakawa T, Yokomaku D, Richards M, Hori H, Adachi N, and Kunugi H. Functional interactions between steroid hormones and neurotrophin BDNF. World Journal of Biological Chemistry. 2010 May 26;1(5):133-43. doi: 10.4331/wjbc.v1.i5.133.
  2. Chiba S, Numakawa T, Ninomiya M, Yoon HS, and Kunugi H. Cabergoline, a dopamine receptor agonist, has an antidepressant-like property and enhances brain-derived neurotrophic factor signaling. Psychopharmacology (Berl) 2010 Aug;211(3):291-301. doi: 10.1007/s00213-010-1894-8. Epub 2010 Jun 5.
  3. Ninomiya M, Numakawa T , Adachi N, Furuta M, Chiba S, Richards M, Shibata S, and Kunugi H. Cortical neurons from intrauterine growth retardation rats exhibit lower response to neurotrophin BDNF. Neurosci Lett. 2010 May 31;476(2):104-9. doi: 10.1016/j.neulet.2010.03.082. Epub 2010 Apr 14.
  4. Kitazawa H, Numakawa T, Adachi N, Kumamaru E, Tuerxun T, Kudo M, Kunugi H. Cyclophosphamide promotes cell survival via activation of intracellular signaling in cultured cortical neurons. Neurosci Lett. 2010 Feb 12;470(2):139-44. doi: 10.1016/j.neulet.2009.12.073. Epub 2010 Jan 5.
  5. Numakawa T, Suzuki S, Kumamaru E, Adachi N, Richards M, Kunugi H. BDNF function and intracellular signaling in neurons. Histol Histopathol. 2010 Feb;25(2):237-58.
  6. Tuerxun T, Numakawa T, Adachi N, Kumamaru E, Kitazawa H, Kudo M, Kunugi H. SA4503, a sigma-1 receptor agonist, prevents cultured cortical neurons from oxidative stress-induced cell death via suppression of MAPK pathway activation and glutamate receptor expression. Neurosci Lett. 2010 Jan 29;469(3):303-8. doi: 10.1016/j.neulet.2009.12.013. Epub 2009 Dec 16.
  7. Kawashima H, Numakawa T, Kumamaru E, Adachi N, Mizuno H, Ninomiya M, Kunugi H, Hashido K. Glucocorticoid attenuates brain-derived neurotrophic factor-dependent upregulation of glutamate receptors via the suppression of microRNA-132 expression. Neuroscience. 2010 Feb 17;165(4):1301-11. doi: 10.1016/j.neuroscience.2009.11.057. Epub 2009 Dec 1.
  8. Hori H, Ozeki Y, Teraishi T, Matsuo J, Kawamoto Y, Kinoshita Y, Suto S, Terada S, Higuchi T, Kunugi H. Relationships between psychological distress, coping styles, and HPA axis reactivity in healthy adults. Journal of Psychiatric Research. 2010 Oct;44(14):865-73. doi: 10.1016/j.jpsychires.2010.02.007. Epub 2010 Mar 23.
  9. Takebayashi M, Hashimoto R, Hisaoka K, Tsuchioka M, Kunugi H. Plasma level of vascularendothelial growth factor and fibroblast growth factor 2 in patients with major depressive disorders. Journal of Neural Transmission. 2010 Sep;117(9):1119-22. doi: 10.1007/s00702-010-0452-1. Epub 2010 Aug 6.
  10. Yazaki S, Koga M, Ishiguro H, Inada T, Ujike H, Itokawa M, Otowa T, Watanabe Y, Someya T, Iwata N, Kunugi H, Ozaki N, Arinami T. An association study between the dymeclin gene and schizophrenia in the Japanese population. Journal of Human Genetics. 2010 Sep;55(9):631-4. doi: 10.1038/jhg.2010.72. Epub 2010 Jun 17.
  11. Ishiguro H, Horiuchi Y, Ishikawa M, Koga M, Imai K, Suzuki Y, Morikawa M, Inada T, Watanabe Y, Takahashi M, Someya T, Ujike H, Iwata N, Ozaki N, Onaivi ES, Kunugi H, Sasaki T, Itokawa M, Arai M, Niizato K, Iritani S, Naka I, Ohashi J, Kakita A, Takahashi H, Nawa H, Arinami T. Brain Cannabinoid CB2 Receptor in Schizophrenia. Biological Psychiatry. 2010 May 15;67(10):974-82. doi: 10.1016/j.biopsych.2009.09.024. Epub 2009 Nov 22.
  12. Amagane H, Watanabe Y, Kaneko N, Nunokawa A, Muratake T, Ishiguro H, Arinami T, Ujike H, Inada T, Iwata N, Kunugi H, Sasaki T, Hashimoto R, Itokawa M, Ozaki N, Someya T. Failure to find an association between myosin heavy chain 9, non-muscle (MYH9) and schizophrenia: a three-stage case-control association study. Schizophrenia Research. 2010 May;118(1-3):106-12. doi: 10.1016/j.schres.2010.01.023. Epub 2010 Feb 26.
  13. Kishi T, Fukuo Y, Kitajima T, Okochi T, Yamanouchi Y, Kinoshita Y, Kawashima K, Inada T, Kunugi H , Kato T, Yoshikawa T, Ujike H, Ozaki N, Iwata N. SIRT1 gene, schizophrenia and bipolar disorder in the Japanese population: an association study. Genes Brain Behav. 2011 Apr;10(3):257-63. doi: 10.1111/j.1601-183X.2010.00661.x. Epub 2010 Nov 22.
  14. Ozeki Y, Pickard BS, Kano SI, Malloy MP, Zeledon M, Sun DQ, Fujii K, Wakui K, Shirayama Y, Fukushima Y, Kunugi H , Hashimoto K, Muir WJ, Blackwood DH, Sawa A. A novel balanced chromosomal translocation found in subjects with schizophrenia and schizotypal personality disorder: altered L-serine level associated with disruption of PSAT1 gene expression. Neuroscience Research. 2011 Feb;69(2):154-60. doi: 10.1016/j.neures.2010.10.003. Epub 2010 Oct 16.
  15. Kishi T, Okochi T, Tsunoka T, Okumura T, Kitajima T, Kawashima K, Yamanouchi Y, Kinoshita Y, Naitoh H, Inada T, Kunugi H, Kato T, Yoshikawa T, Ujike H, Ozaki N, Iwata N. Serotonin 1A receptor gene, schizophrenia and bipolar disorder: An association study and meta-analysis. Psychiatry Research. 2011 Jan 30;185(1-2):20-6. doi: 10.1016/j.psychres.2010.06.003. Epub 2010 Jul 1.
  16. Furuse T, Wada Y, Hattori K , Yamada I, Kushida T, Shibukawa Y, Masuya H, Kaneda H, Miura I, Seno N, Kanda T, Hirose R, Toki S, Nakanishi K, Kobayashi K, Sezutsu H, Gondo Y, Noda T, Yuasa S, Wakana S. Phenotypic characterization of a new Grin1 mutant mouse generated by ENU mutagenesis. Eur J Neurosci. 2010 Apr;31(7):1281-91. doi: 10.1111/j.1460-9568.2010.07164.x. Epub 2010 Mar 19.
  17. Chiba S, Numakawa T, Ninomiya M, Yoon HS , and Kunugi H. Cabergoline, a dopamine receptor agonist, has an antidepressant-like property and enhances brain-derived neurotrophic factor signaling. Psychopharmacology (Berl). 2010 Aug;211(3):291-301. doi: 10.1007/s00213-010-1894-8. Epub 2010 Jun 5.
  18. Ota M, Nemoto K, Sato N, Mizukami K, Yamashita F, Asada T. Relationship between white matter T2 hyperintensity and cortical volume changes on magnetic resonance imaging in healthy elders. Int J Geriatr Psychiatry. 2011 Sep;26(9):886-92. doi: 10.1002/gps.2618. Epub 2010 Sep 24.
  19. Nemoto K, Mizukami K, Hori T, Tachikawa H, Ota M , Takeda T, Ohnishi T, Matsuda H, Asada T. Hyperperfusion in primary somatosensory region related to somatic hallucination in the elderly. Psychiatry Clin Neurosci. 2010 Aug;64(4):421-5. doi: 10.1111/j.1440-1819.2010.02101.x. Epub 2010 Jun 10.
  20. Ozeki Y, Fujii K, Kurimoto N, Yamada N, Okawa M, Aoki T, Takahashi J, IshidaN, Horie M, Kunugi H. QTc prolongation and antipsychotic medications in a sample of 1017 patients with schizophrenia. Prog Neuropsychopharmacol Biol Psychiatry. 2010 Mar 17;34(2):401-5. doi: 10.1016/j.pnpbp.2010.01.008. Epub 2010 Jan 15.
  21. Hori H, Ozeki Y, Teraishi T, Matsuo J, Kawamoto Y, Kinoshita Y, Suto S, Terada S, Higuchi T, Kunugi H. Relationships between psychological distress, coping styles, and HPA axis reactivity in healthy adults. J Psychiatr Res. 2010 Oct;44(14):865-73. doi: 10.1016/j.jpsychires.2010.02.007. Epub 2010 Mar 23.
  22. Furuta M, Fukushima A, Chiba S , Sano A, Akema T, Kimura F, Funabashi T. Progesterone receptor immunoreactivity in the brains of ovariectomized aged rats. Neuroreport. 2010 Aug 4;21(11):777-81. doi: 10.1097/WNR.0b013e32833c5b6f.
  23. Ahmed Z, Sheng H, Xu YF, Lin WL, Innes AE, Yu X, Hou H, Chiba S, Yamanouchi K, Petrucelli L, Nishihara M, Hutton ML, McGowan E, Dickson DW, Lewis J. Accelerated lipofuscinosis and ubiquitination in granulin knockout mice suggests a role for progranulin in successful aging. Am J Pathol. 2010 Jul;177(1):311-24. doi: 10.2353/ajpath.2010.090915. Epub 2010 Jun 3.

2010 著書・訳書

  1. 太田 深秀 , 功刀 浩他 :精神疾患診断のための脳形態・機能検査法(功刀 浩編) 新興医学出版社,東京
  2. 太田 深秀 , 功刀 浩他 :精神医学・心理学・精神看護学辞典(高橋修一編) 照林社, 東京

2010 総説

  1. Fukuo Y, Kishi T, Yoshimura R, Kitajima T, Okochi T, Yamanouchi Y, Kinoshita Y, Kawashima K, Naitoh H, Umene-Nakano W, Inada T, Kunugi H, Kato T, Yoshikawa T, Ujike H, Nakamura J, Ozaki N, Iwata N. Serotonin 6 receptor gene and mood disorders: case-control study and meta-analysis. Neuroscience Research. 2010 Jul;67(3):250-5. doi: 10.1016/j.neures.2010.04.003. Epub 2010 Apr 13.
  2. Kunugi H, Hori H, Adachi N, and Numakawa T. Interface between hypothalamic-pituitary-adrenal axis and brain-derived neurotrophic factor in depression. Psychiatry Clin Neurosci. 2010 Oct;64(5):447-59. doi: 10.1111/j.1440-1819.2010.02135.x.
  3. 藤井 崇,功刀 浩 大うつ病性障害とエンドフェノタイプとしてのHPA系の遺伝子解析 (特集: 精神疾患の遺伝子は,本当にみつかったのか?) 分子精神医学 2010; 10巻 1号 (通号 38): 33-39
  4. 功刀 浩: うつ病におけるストレスと神経栄養因子の役割.鳥取臨床科学研究会誌 3 (1): 76-82, 2010.
  5. 尾崎 紀夫,笠井 清登,加藤 忠史,神庭 重信,功刀 浩,久保 千春,小山 司,白川 治,西田 淳志,野村 総一郎,福田 正人,元村 直靖,山脇 成人: うつ病対策の総合的提言.日本生物学的精神医学会誌 21(3): 155-182, 2010.
  6. 功刀 浩 :ドーパミンの威力と魔力 (連載:心理臨床家のための脳科学講義9).臨床心理学 10 (6): 904-910, 2010. ( 2010 年 11 月)
  7. 功刀 浩 :うつ病におけるモノアミンと神経栄養因子 (連載:心理臨床家のための脳科学講義8).臨床心理学 10 (5) :750-758, 2010. ( 2010 年9月)
  8. 功刀 浩 :うつ病におけるストレスホルモンの役割 (連載:心理臨床家のための脳科学講義7).臨床心理学 10 (4) :583-589, 2010. ( 2010 年7月)
  9. 功刀 浩 :抗うつ薬の作用メカニズムからみたうつ病の病態.(特集 うつ病の分子メカニズム) Medical Bio 7 (4): 26-33, 2010. ( 2010 年 7 月 1 日)
  10. 功刀 浩 :近年注目されている統合失調症の仮説について. ( 特集 統合失調症 ) こころのりんしょう a ・ la・carte 29 (2): 215-220, 2010. ( 2010 年 6 月)
  11. 功刀 浩 :ドーパミンとその統合失調症における役割.(連載:心理臨床家のための脳科学講義 6 )臨床心理学 10 (3) : 429-434, 2010. ( 2010 年5月)
  12. 功刀 浩 :ストレスホルモンと恐怖記憶―トラウマの脳科学 (連載:心理臨床家のための脳科学講義 11 ).臨床心理学 11 (2): 247-253, 2011. ( 2011 年 3 月)
  13. 功刀 浩 :統合失調症と遺伝―環境相互作用.精神科 18 (1): 19-24, 2011. (2011年 1月)
  14. 功刀 浩 :ストレスホルモン不足 (連載:心理臨床家のための脳科学講義 10 ).臨床心理学 11 (1): 93-99, 2011. ( 2011 年 1 月)
  15. 沼川 忠広, 功刀 浩  相互作用するストレスホルモン(グルココルチコイド)と BDNF 機能. 生化学 社団法人日本生化学会、 2010. p419 − 422
  16. 功刀 浩 , 千葉秀一 , 堀 弘明 , 沼川忠広  治療抵抗性うつ病に対するドパミン受容体作動薬の有用性に関する検討 Depression Frontier 、医薬ジャ - ナル社、 2010. p85-90
  17. Baharnoori M, Bartholomeusz C, Boucher AA, Buchy L, Chaddock C, Chiliza B, Focking M, Fornito A, Gallego JA, Hori H , Huf G, Jabbar GA, Kang SH, El Kissi Y, Merchan-Naranjo J, Modinos G, Abdel-Fadeel NA, Neubeck AK, Ng HP, Novak G, Owolabi OO, Prata DP, Rao NP, Riecansky I, Smith DC, Souza RP, Thienel R, Trotman HD, Uchida H, Woodberry KA, O'Shea A, DeLisi LE. The 2nd Schizophrenia International Research Society Conference, 10-14 April 2010, Florence, Italy: summaries of oral sessions. Schizophr Res. 124: e1-62,
  18. 沼川忠広: グルココルチコイド受容体およびBDNF受容体の相互作用に制御されるグルタミン酸放出. (Glucocorticoid receptor interaction with TrkB promotes BDNF-triggered glutamate release.) 日本神経化学会奨励賞総説, 2010.