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研 究 業 績 

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2009

Matsumoto H, Maruse H, Sasazaki S, Fujiwara A, S Takeda, Ichihara N, Kikuchi T, Mukai F, Mannen H: Expression pattern of WWP1 in muscular dystrophic and normal chickens. J. Poult. Sci. 46: 95-99, 2009

Kobayashi M, Nakamura A, Hasegawa D, Fujita M, Orima H, Takeda S: Evaluation of dystrophic dog pathology by fat-suppressed T2-weighted imaging. Muscle Nerve.40: 815-826, 2009

Cui R, Duan XL, Anderson GJ, Qiao YT, Yu P, Qian ZM, Yoshida K, Takeda S, Guo P, Yang ZL, Chang YZ : Age-dependent expression of hephaestin in the brain of ceruloplasmin-deficient mice. J Trace Elem Med Biol. 23: 290-299, 2009

Guo P, Cui R, Chang YZ, Wu WS, Qian ZM, Yoshida K, Qiao YT, Takeda S, Duan XL: Hepcidin, an antimicrobial peptide is downregulated in ceruloplasmin-deficient mice. Peptides. 30: 262-266, 2009

Katsube K, Ichikawa S, Katsuki Y, Kihara T, Terai M, Lau LF, Tamamura Y, Takeda S, Umezawa ; A, Sakamoto K, Yamaguchi A: CCN3 and bone marrow cells. J Cell Commun Signal. 3: 135-145, 2009

Okada T, Nonaka-Sarukawa M, Uchibori R, Kinoshita K, Hayashita-Kinoh H, Nitahara-Kasahara Y, Takeda S, Ozawa K: Scalable purification of AAV1 and AAV8 vectors using dual ion-exchange adsorptive membranes.  Hum Gene Ther.20: 1013-1021,  2009

Nakao R, Hirasaka K, Goto J, Ishidoh K, Yamada C, Ohno A, Okumura Y, Nonaka I, Yasutomo K, Baldwin KM, Kominami E, Higashibata A, Nagano K, Tanaka K, Yasui N, Mills EM, Takeda S, Nikawa T: Ubiquitin ligase Cbl-b is a negative regulator for IGF-1 signaling during muscle atrophy caused by unloadingMol Cell Biol. 17: 4798-4811, 2009

Nakamura A, Takeda S: Exon-skipping therapy for Duchenne muscular dystrophy.  Neuropathology. 29: 494-501, 2009

Uchibori R, Okada T, Ito T, Urabe M, Mizukami H, Kume A, Ozawa K: Retroviral vector-producing mesenchymal stem cells for targeted suicide cancer gene therapy. J Gene Med. 11: 373-381, 2009

Yokota T, Lu QL, Partridge T, Kobayashi M, Nakamura A, Takeda S, Hoffman E: Efficacy of systemic morpholino exon-skipping in duchenne dystrophy dogs. Ann Neurol 65: 667-676, 2009

Chang H, Yoshimoto M, Umeda K, Iwasa T, Mizuno Y, Fukada SI, Yamamoto H, Motohashi N, Suzuki Y, Takeda S, Heike T, Nakahata T:
Generation of transplantable, functional satellite-like cells from mouse embryonic stem cells. FASEB J
23: 1907-1919, 2009

Yokota T, Takeda S, Lu QL, Partridge TA, Nakamura A, Hoffman EP:
A renaissance for antisense oligonucleotide drugs in neurology: exon skipping breaks new ground. Arch Neurol 66: 32-38, 2009

Miyazaki D, Yoshida K, Fukushima K, Nakamura A, Suzuki K, Sato T, Takeda S, Ikeda S:
Characterization of deletion breakpoints in patients with dystrophinopathy carrying a deletion of exons 45-55 of the Duchenne muscular dystrophy (DMD) gene.
J Hum Genet 54: 127-130, 2009

Miyagoe-Suzuki Y, Masubuchi N, Miyamoto K, Wada MR, Yuasa S, Saito F, Matsumura K, Kanesaki H, Kudo A, Manya H, Endo T, Takeda S
: Reduced proliferative activity of primary POMGnT1-null myoblasts in vitro. Mech Dev 126: 107-116, 2009

Kanagawa M, Nishimoto A, Chiyonobu T, Takeda S, Miyagoe-Suzuki Y, Wang F, Fujikake N, Taniguchi M, Lu Z, Tachikawa M, Nagai Y, Tashiro F, Miyazaki J, Tajima Y, Takeda S, Endo T, Kobayashi K, Campbell KP, Toda T:
Residual laminin-binding activity and enhanced dystroglycan glycosylation by LARGE in novel model mice to dystroglycanopathy. Hum Mol Genet 18: 621-31, 2009

Sekiguchi M, Zushida K, Yoshida M, Maekawa M, Kamichi S, Yoshida M, Sahara Y, Yuasa S, Takeda S, Wada K:
A deficit of brain dystrophin impairs specific amygdala GABAergic transmission and enhances defensive behaviour in mice. Brain 132: 124-135, 2009

Ohshima S, Shin JH, Yuasa K, Nishiyama A, Kira J, Okada T, Takeda S:
Transduction Efficiency and Immune Response Associated With the Administration of AAV8 Vector Into Dog Skeletal Muscle. Mol Ther 17: 73-80, 2009

Shibuya N, Tanaka M, Yoshida M, Ogasawara Y, Togawa T, Ishii K and Kimura H
: 3-mercaptopyruvate sulfurtransferase produces hydrogen sulfide and bound sulfane sulfur in the brain. Antioxid Redox Signal 11: 703-714, 2009


2008

Segawa M, Fukada S, Yamamoto Y, Yahagi H, Kanematsu M, Sato M, Ito T, Uezumi A, Hayashi S, Miyagoe-Suzuki Y, Takeda S, Tsujikawa K, Yamamoto H:
Suppression of macrophage functions impairs skeletal muscle regeneration with severe fibrosis. Exp Cell Res 314: 3232-3244, 2008

Yuasa K, Hagiwara Y, Ando M, Nakamura A, Takeda S, Hijikata T:
MicroRNA-206 is highly expressed in newly formed muscle fibers: implications regarding potential for muscle regeneration and maturation in muscular dystrophy. Cell Struct Funct 33: 163-169, 2008

Katsumata O, Honma T, Sanda M, Kamata A, Takeda S, Kondo H, Sakagami H:
Predominant localization of EFA6A, a guanine nucleotide exchange factor for ARF6, at the perisynaptic photoreceptor processes. Brain Res 1234:44-49, 2008

Motohashi N, Uezumi A, Yada E, Fukada S, Fukushima K, Imaizumi K, Miyagoe-Suzuki, Y, Takeda S:
Muscle CD31(-) CD45(-) side population cells promote muscle regeneration by stimulating proliferation and migration of myoblasts. Am J Pathol 173: 781-791, 2008

Sato K, Yokota T, Ichioka S, Shibata M, Takeda S:
Vasodilation of intramuscular arterioles under shear stress in dystrophin-deficient skeletal muscle is impaired through decreased nNOS expression. Acta Myol 27:30-36, 2008

Nishiyama A, Ampong BN, Ohshima S, Shin JH, Nakai H, Imamura M, Miyagoe-Suzuki Y, Okada T, Takeda S:
Recombinant adeno-associated virus type 8-mediated extensive therapeutic gene delivery into skeletal muscle of alpha-sarcoglycan-deficient mice. Hum Gene Ther 19: 719-730, 2008

Nakamura A, Yoshida K, Fukushima K, Ueda H, Urasawa N, Koyama J, Yazaki Y, Yazaki M, Sakai T, Haruta S, Takeda S, Ikeda S
: Follow-up of three patients with a large in-frame deletion of exons 45-55 in the Duchenne muscular dystrophy (DMD) gene. J Clin Neurosci 15: 757-763, 2008

Hijikata T, Nakamura A, Isokawa K, Imamura M, Yuasa K, Ishikawa R, Kohama K,@Takeda S, Yorifuji H:
Plectin 1 links intermediate filaments to costameric sarcolemma through {beta}-synemin, {alpha}-dystrobrevin and actin. J Cell Sci 121: 2062-2074, 2008

Matsumoto H, Maruse H, Inaba Y, Yoshizawa K, Sasazaki S, Fujiwara A, Nishibori M, Nakamura A, Takeda S, Ichihara N, Kikuchi T, Mukai F, Mannen H:
The ubiquitin ligase gene (WWP1) is responsible for the chicken muscular dystrophy. FEBS Lett 582: 2212-2218, 2008

Urasawa N, Wada MR, Machida N, Yuasa K, Shimatsu Y, Wakao Y, Yuasa S, Sano T, Nonaka I, Nakamura A, Takeda S:
Selective vacuolar degeneration in dystrophin deficient canine Purkinje fibers despite preservation of dystrophin-associated proteins with overexpression of Dp71. Circulation 117: 2437-2448, 2008

Tanihata J, Suzuki N, Miyagoe-Suzuki Y, Imaizumi K, Takeda S:
Dowmstream utrophin enhancer is required for expression of utrophin in skeletal muscle. J Gene Med 10: 702-713, 2008

Nakatani M, Takehara Y, Sugino H, Matsumoto M, Hashimoto O, Hasegawa Y, Murakami T, Uezumi A, Takeda S, Noji S, Sunada Y, Tsuchida K:
Transgenic expression of a myostatin inhibitor derived from follistatin increases skeletal muscle mass and ameliorates dystrophic pathology in mdx mice. FASEB J 22: 477-487, 2008

Yuasa K, Nakamura A, Hijikata T, Takeda S:
Dystrophin deficiency in canine X-linked muscular dystrophy in Japan (CXMDJ) alters myosin heavy chain expression profiles in the diaphragm more markedly than in the tibialis cranialis muscle. BMC Musculoskelet Disord 9: 1, 2008

Fukada S, Yamamoto Y, Segawa M, Sakamoto K, Nakajima M, Sato M, Morikawa D, Uezumi A, Miyagoe-Suzuki Y, Takeda S, Tsujikawa K, Yamamoto H: CD90-positive cells, an additional cell population, produce laminin <alpha>2 upon transplantation to dy3k/dy3k mice. Exp Cell Res 314: 193-203, 2008



2007

Suzuki N, Motohashi N, Uezumi A, Fukada SI, Yoshimura T, Itoyama Y, Aoki M, Miyagoe-Suzuki Y, Takeda S. NO production results in suspension-induced muscle atrophy through dislocation of neuronal NOS. J Clin Invest.117(9): 2468-2476, 2007

Ikemoto M, Fukada SI, Uezumi A, Masuda S, Miyoshi H, Yamamoto H, Wada MR, Masubuchi N, Miyagoe-Suzuki Y, Takeda S. Autologous Transplantation of SM/C-2.6(+) Satellite Cells Transduced with Micro-dystrophin CS1 cDNA by Lentiviral Vector into mdx Mice. Mol Ther. 15(12): 2178-85, 2007

Fukada S, Uezumi A, Ikemoto M, Masuda S, Segawa M, Tanimura N, Yamamoto H, Miyagoe-Suzuki Y, Takeda S. Molecular Signature of Quiescent Satellite Cells In Adult Skeletal Muscle. Stem Cells 25(10): 2448-2459, 2007

Hirasaka K, Kohno S, Goto J, Furochi H, Mawatari K, Harada N, Hosaka T, Na kaya Y, Ishidoh K, Obata T, Ebina Y, Gu H, Takeda S, Kishi K, Nikawa T. Deficiency of Cbl-b gene enhances infiltration and activation of macrophages in adipose tissue and causes peripheral insulin resistance in mice. Diabetes 56(10): 2511-2522, 2007

Yuasa K, Yoshimura M, Urasawa N, Ohshima S, Howell JM, Nakamura A, Hijikata T, Miyagoe-Suzuki Y, Takeda S. Injection of a recombinant AAV serotype 2 into canine skeletal muscles evokes strong immune responses against transgene products. Gene Ther. 14(17): 1249-1260, 2007

Fukushima K, Nakamura A, Ueda H, Yuasa K, Yoshida K, Takeda S, Ikeda SI. Activation and localization of matrix metalloproteinase-2 and -9 in the skeletal muscle of the muscular dystrophy dog (CXMDJ).BMC Musculoskelet Disord. 8(1): 54

Oyama T, Nagai T, Wada H, Naito AT, Matsuura K, Iwanaga K, Takahashi T, Goto M, Mikami Y, Yasuda N, Akazawa H, Uezumi A, Takeda S, Komuro I. Cardiac side population cells have a potential to migrate and differentiate into cardiomyocytes in vitro and in vivo. J Cell Biol. 176(3): 329-341, 2007

Ideno J, Mizukami H, Kakehashi A, Saito Y, Okada T, Urabe M, Kume A, Kuroki M, Kawakami M, Ishibashi S, Ozawa K: Prevention of diabetic retinopathy by intraocular soluble flt-1 gene transfer in a spontaneously diabetic rat model. Int J Mol Med 19 (1): 75-79, 200

Takei Y, Mizukami H, Saga Y, Yoshimura I, Hasumi Y, Takayama T, Kohno T, Matsushita T, Okada T, Kume A, Suzuki M, Ozawa K: Suppression of ovarian cancer by muscle-mediated expression of soluble VEGFR-1/Flt-1 using adeno-associated virus serotype 1-derived vector. Int J Cancer 120 (2): 278-284, 2007

Nakata M, Okada T, Ozawa K, Yada T: Resistin induces insulin resistance in pancreatic islets to impair glucose-induced insulin release. Biochem Biophys Res Commun 353 (4): 1046-1051, 2007

Liu Y, Okada T, Nomoto T, Ke X, Kume A, Ozawa K, Xiao S: Promoter effects of adeno-associated viral vector for transgene expression in the cochlea in vivo. Exp Mol Med. 39 (2): 170-175, 2007

Ito T, Okada T, Miyashita H, Nomoto T, Nonaka-Sarukawa M, Uchibori R, Maeda Y, Urabe M, Mizukami H, Kume A, Takahashi M, Ikeda U, Shimada K, Ozawa K: Interleukin-10 expression mediated by an adeno-associated virus vector prevents monocrotaline-induced pulmonary arterial hypertension in rats. Circ Res. 101 (7): 734-741, 2007

Ito T, Okada T, Mimuro J, Miyashita H, Uchibori R, Urabe M, Mizukami H, Kume A, Takahashi M, Ikeda U, Sakata Y, Shimada K, Ozawa K: Adeno associated virus-mediated prostacyclin synthase expression prevents pulmonary arterial hypertension in rats. Hypertension 50 (3): 531-536, 2007

Kobayashi M, Okada T, Murakami T, Ozawa K, Kobayashi E Morita T: Tissue-targeted in vivo gene transfer coupled with histone deacetylase inhibitor depsipeptide (FK228) enhances adenoviral infection in rat renal cancer allograft model systems. Urology 70 (6): 1230-1236, 2007


2006


Yugeta N, Urasawa N, Fujii Y, Yoshimura M, Yuasa K, Nakamura A, Wada MR, Nakura M, Shimatsu Y, Tomohiro M,Takahashi A, Machida N, Wakao Y, Takeda S. Cardiac involvement in Beagle-based canine X-linked muscular dystrophy in Japan (CXMDJ): electrocardiographic, echocardiographic, and morphologic studies. BMC Cardiovasc Disord. 6: 47, 2006

Pramono ZA, Lai PS, Tan CL, Takeda S, Yee WC. Identification and characterization of a novel human dysferlin transcript: dysferlin_v1. Hum Genet. 120 (3): 410-419, 2006

Yokota T, Lu QL, Morgan JE, Davies KE, Fisher R, Takeda S, Partridge TA. Expansion of revertant fibers in dystrophic mdx muscles reflects activity of muscle precursor cells and serves as an index of muscle regeneration. J Cell Sci. 119 (Pt 13): 2679-2687, 2006

Suzue N, Nikawa T, Onishi Y, Yamada C, Hirasaka K, Ogawa T, Furochi H, Ksaka H, Ishidoh K, Gu H, Takeda S, Ishimaru N, Hayashi Y. Yamamoto H, Kishi K, Yasui N: Ubiquitin ligase Cbl-b down-regulate bone formation through supression of OGF-1 signaling in osteblasts during denervation. J Bone Miner Res. 21(5): 722-734, 2006

Shiga K, Yoshioka H, Matsumiya T, Kimura I, Takeda S, Imamura M. zeta-Sarcoglycan is a functional homologue of gamma-sarcoglycan in the formation of the sarcoglycan complex. Exp Cell Res. 312 (11): 2083-2092, 2006

Uezumi A, Ojima K, Fukada S, Ikemoto M, Masuda S, Miyagoe-Suzuki Y, Takeda S. Functional heterogeneity of side population cells in skeletal muscle. Biochem Biophys Res Commun 341: 864-873, 2006

Hagiwara Y, Fujita M, Imamura M, Noguchi S, Sasaoka T: Caveolin-3 deficiency decreases the gene expression level of osteopontin in mdx mouse skeletal muscle. Acta Myol. 25, 53-61, 2006


2005

Okano T, Yoshida K, Nakamura A, Sasazawa F, Oide T, Takeda S, Ikeda S. Chronic exercise accelerates the degeneration-regeneration cycle and downregulates insulin-like growth factor-1 in muscle of mdx mice. Muscle Nerve 32 (2): 191-199, 2005

Dezawa M, Ishikawa H, Itokazu Y, Yoshihara T, Hoshino M, Takeda S, Ide C, Nabeshima Y. Bone marrow stromal cells generate muscle cells and repair muscle degeneration. Science 309 (5732): 314-317, 2005

Nakamura A, Yoshida K, Ueda H, Takeda S, Ikeda S. Up-regulation of mitogen activated protein kinases in mdx skeletal muscle following chronic treadmill exercise. Biochim Biophys Acta. 1740 (3): 326-331, 2005

Mochizuki Y, Ojima K, Uezumi A, Masuda S, Yoshimura K, Takeda S. Participation of bone marrow-derived cells in fibrotic changes in denervated skeletal muscle. Am J Pathol. 166 (6): 1721-1732, 2005

Yang D, Bierman J, Tarumi YS, Zhong YP, Rangwala R, Proctor TM, Miyagoe-Suzuki Y, Takeda S, Miner JH, Sherman LS, Gold BG, Patton BL. Coordinate control of axon defasciculation and myelination by laminin-2 and -8. J Cell Biol. 168 (4): 655-666, 2005

Imamura M, Mochizuki Y, Engvall E, Takeda S. {epsilon}-Sarcoglycan compensates for lack of {alpha}-sarcoglycan in a mouse model of limb-girdle muscular dystrophy. Hum Mol Genet. 14 (6): 775-783, 2005

Takahashi J, Itoh Y, Fujimori K, Imamura M, Wakayama Y, Miyagoe-Suzuki Y, Takeda S. The utrophin promoter A drives high expression of the transgenic LacZ gene in liver, testis, colon, submandibular gland, and small intestine. J Gene Med. 7 (2): 237-248, 2005

Lu QL, Rabinowitz A, Chen YC, Yokota T, Yin H, Alter J, Jadoon A, Bou-Gharios G, Partridge T. Systemic delivery of antisense oligoribonucleotide restores dystrophin expression in body-wide skeletal muscles. Proc Natl Acad Sci U S A. 102 (1): 198-203, 2005

Shimatsu Y, Yoshimura M, Yuasa K, Urasawa N, Tomohiro M, Nakura M, Tanigawa M, Nakamura A, Takeda S: Major clinical and histopathological characteristics of canine X-linked muscular dystrophy in Japan, CXMDJ. Acta Myologica XXIV: 145-154, 2005

Ampong BN, Imamura M, Matsumiya T, Yoshida M, Takeda S: Instracellular localization of dysferlin and its association with the dihydropyridine receptor. Acta Myologica XXIV: 134-144, 2005

Hoshino Y, Uchida M, Shimatsu Y, Miyake M, Nagao Y, Minami N, Yamada M, Imai H: Developmental competence of somatic cell nuclear transfer embryos reconstructed from oocytes matured in vitro with follicle shells in miniature pig. Cloning Stem Cells 7: 17-26, 2005

Ozawa E, Mizuno Y, Hagiwara Y, Sasaoka T, Yoshida M: Molecular and cell biology of the sar coglycan complex. Muscle Nerve 32: 563-576, 2005


2004
Yoshimura M, Sakamoto M, Ikemoto M, Mochizuki Y, Yuasa K, Miyagoe-Suzuki Y, Takeda S. AAV vector-mediated microdystrophin expression in a relatively small percentage of mdx myofibers improved the mdx phenotype. Mol Ther. 10 (5): 821-828, 2004

Hara H, Monsonego A, Yuasa K, Adachi K, Xiao X, Takeda S, Takahashi K, Weiner HL, Tabira T. Development of a safe oral Abeta vaccine using recombinant adeno-associated virus vector for Alzheimer's disease. J Alzheimers Dis. 6 (5): 483-488, 2004

Ojima K, Uezumi A, Miyoshi H, Masuda S, Morita Y, Fukase A, Hattori A, Nakauchi H, Miyagoe-Suzuki Y, Takeda S. Mac-1(low) early myeloid cells in the bone marrow-derived SP fraction migrate into injured skeletal muscle and participate in muscle regeneration. Biochem Biophys Res Commun. 2004 321 (4): 1050-1061, 2004

Gawlik K, Miyagoe-Suzuki Y, Ekblom P, Takeda S, Durbeej M. Laminin alpha1 chain reduces muscular dystrophy in laminin alpha2 chain deficient mice. Hum Mol Genet. 13 (16): 1775-1784, 2004

Nishiyama A, Endo T, Takeda S, Imamura M. Identification and characterization of epsilon-sarcoglycans in the central nervous system. Brain Res Mol Brain Res. 125 (1-2): 1-12. 2004

Fukada S, Higuchi S, Segawa M, Koda K, Yamamoto Y, Tsujikawa K, Kohama Y, Uezumi A, Imamura M, Miyagoe-Suzuki Y, Takeda S, Yamamoto H. Purification and cell-surface marker characterization of quiescent satellite cells from murine skeletal muscle by a novel monoclonal antibody. Exp Cell Res. 296 (2): 245-255, 2004

Yuasa K, Fukumoto S, Kamasaki Y, Yamada A, Fukumoto E, Kanaoka K, Saito K, Harada H, Arikawa-Hirasawa E, Miyagoe-Suzuki Y, Takeda S, Okamoto K, Kato Y, Fujiwara T. Laminin alpha2 is essential for odontoblast differentiation regulating dentin sialoprotein expression. J Biol Chem. 279 (11): 10286-10292, 2004.

Munehira Y, Ohnishi T, Kawamoto S, Furuya A, Shitara K, Imamura M, Yokota T, Takeda S, Amachi T, Matsuo M, Kioka N, Ueda K: Alpha1-syntrophin modulates turnover of ABCA1. J Biol Chem. 279 (15): 15091-15095, 2004

Nikawa T, Ishidoh K, Hirasaka K, Ishihara I, Ikemoto M, Kano M, Kominami E, Nonaka I, Ogawa T, Adams G, Baldwin K, Yasui N, Kishi K, Takeda S: Skeletal muscle gene expression in space-flown rats. FASEB J. 18 (3): 522-5242004

Ishikawa-Sakurai M, Yoshida M, Imamura M, Davies KE, Ozawa E: ZZ domain is essentially required for the physiological binding of dystrophin and utrophin to beta-dystroglycan. Hum Mol Genet 13: 693-702, 2004

Mizuno Y, Guyon JR, Watkins SC, Mizushima K, Sasaoka T, Imamura M, Kunkel LM, Okamoto K: beta-Synemin localizes to regions of high stress in human skeletal myofibers. Muscle Nerve 30: 337-346, 2004

Shimatsu Y, Uchida M, Niki R, Imai H: Effects of a synthetic progestogen, altrenogest, on oestrus synchronisation and fertility in miniature pigs. Vet Rec 155: 633-635, 2004




著 書

Okada T, Takeda S: Gene therapy for Duchenne muscular dystrophy. in A Guide to Human Gene Therapy (ed. by Roland W. Herzog and Sergei Zolotukhin), World Scientific, NJ; in press

Miyagoe-Suzuki Y, Uezumi A, Takeda S: Side Population (SP) cells and skeletal muscle differentiation. Recent advances of skeletal muscle differentiation, Research Signpost, 378/661 (2), Fort P.O., Trivandrum-695 023, Kerala, India, 2008

武田伸一: 筋ジストロフィー治療法研究の進歩. こころの健康科学研究の現状と課題 3.3: 315-327, 2007

武田伸一: ジストロフィン欠損における新たな分子病態. 小児神経学の進歩 第36集: 132-138, 2007

鈴木友子,武田伸一:筋ジストロフィーの治療を目指して, 先進・脳神経科学,監修:高坂新一,編著:中村俊,培風館:174-187, 2006

総 説

2009

Ito N, Miyagoe-Suzuki Y: Neuronal NOS as a regulator of muscle mass. Editor: Yoshinobu Ohira. Muscle Cell Physiology, Research Signpost, Fort P.O., Trivandrum-695 023, Kerala, India, in press, 2009

矢田英理香, 武田伸一: iPS細胞を用いた筋ジストロフィー治療の展望 難病と在宅ケアin press, 2009


2008

Miyagoe-Suzuki Y, Uezumi A, Takeda S: Side population (SP) cells and skeletal muscle differentiation Recent Advances of Skeletal Muscle Differentiation Editors: Kunihiro Tsuchida and Shin’ichi Takeda. Research Signpost 378/661(2) Fort P.O., Trivandrum-695 023, Kerala, India, 2008

Okada T, Ozawa K: Vector-producing tumor-tracking multipotent mesenchymal stromal cells for suicide cancer gene therapy. Front Biosci 13: 1887-1891, 2008.

Ozawa K., Sato K., Oh I, Ozaki K., Uchibori R, Obara Y, Kikuchi Y, Ito T, Okada T, Urabe M, Mizukami H, Kume A. Cell and gene therapy using mesenchymal stem cells (MSCs). J Autoimmun 30: 121-127, 2008

小林正典, 武田伸一: 筋ジストロフィーの遺伝子治療.総合リハビリテーション36: 1043-1049, 2008

齊藤崇, 武田伸一: 高齢者の筋ジストロフィー/多発性筋炎のケアModern Physician: 28, 656-660, 2008

笠原優子、岡田尚巳、武田伸一: ウイルスベクターを用いた筋ジストロフィーの治療法開発 医学のあゆみ 226: 379-383, 2008

武田伸一:デュシェンヌ型筋ジストロフィーの治療 財団法人 精神・神経科学振興財団 News Letter No.3, 2008

吉村まどか, 武田伸一: 筋ジストロフィー・ミオパチー 総合臨床 57: 606-608, 2008

深田宗一朗, 鈴木 友子, 武田 伸一: 筋ジストロフィーの治療とケア:筋衛星細胞の維持 活性化と自己複製の制御機構. 難病と在宅ケア 14: 50-52, 2008

岡田尚巳: 間葉系幹細胞を利用した癌遺伝子治療 最新医学63: 64-71, 2008

吉田幹晴: サルコグリカノパチー. Clinical Neuroscience(臨床神経科学)26: 152-153, 2008


2007

Naoki Suzuki, Yuko Miyagoe-Suzuki, Shin’ichi Takeda. Gene Therapy for Duchenne Muscular Dystrophy Future Neurology, Vol. 2(1), 87-96, 2007

武田伸一: 国立精神・神経センターにおける筋ジストロフィー研究の成果. 週刊社会保障, No.2426: 31, 2007

Suzuki N, Miyagoe-Suzuk Y, Takeda S: Gene therapy for Duchenne muscular dystrophy. Future Neurology 2(1): 87-96, 2007

湯浅勝敏, 土方貴雄, 武田伸一: 筋ジストロフィーの遺伝子治療における骨格筋への遺伝子デリバリー. Drug Delivery System 22(2): 140-147, 2007

西山章代, 武田伸一: 骨格筋へのin vivo 遺伝子導入. バイオテクノロジージャーナル 7: 183-187, 2007

本橋紀夫, 武田伸一: 筋肉の再生. THE BONE 21(4): 61-64, 2007

辛鎮洪, 武田伸一: 筋ジストロフィーの治療戦略. BRAIN and NERVE 59(4): 415-424, 2007

吉田幹晴:ジストロフィン複合体におけるタンパク質間相互作用. 生体の科学 58(5): 440-441, 2007


2006

松尾雅文、武田伸一 : 最近分かった筋ジストロフィーの病態と治療. 脳と発達 38(2) : 129-131, 2006

横田俊文、武田伸一 : 筋ジストロフィーに対する遺伝子治療の試み. 医学のあゆみ 216(10) : 743-747, 2006

上住聡芳,鈴木直輝,武田伸一: 筋疾患の病態と診断, 治療戦略の最前線, 筋ジストロフィーの再生医療, 小児科診療・第69巻・4号:570-574, 2006

西山章代,武田伸一: 筋ジストロフィーのモデル動物と遺伝子治療, Current Insights in Neurological Science VOL.14 No.1: 8-9, 2006

西山章代,武田伸一: 骨格筋組織への in vivo遺伝子導入, BIOバイオテクノロジージャーナル VOl.7 No.2, 3-4 : 183-187, 2006


2005

大島幸子、武田伸一: 筋ジストロフィーの動物の心筋障害.神経内科 62(6):539-546, 2005

吉村まどか、武田伸一: 筋ジストロフィーの遺伝子治療.BRAIN MEDICAL 17(3):221-228, 2005

西山章代、武田伸一: 筋ジストロフィーのモデル動物と遺伝子治療.Neurological Science 14(1):8-9, 2005

武田伸一、鈴木友子: 筋ジストロフィーの発症メカニズムと治療研究. -疾患解明Overview- 実験医学 23(10):1590-1596, 2005

吉田幹晴: ジストログリカン複合体とサルコグリカン複合体(DAG1, SGC). 生体の科学  56(5):486-487, 2005


2004

武田伸一: 筋ジストロフィーモデル動物における遺伝子治療研究の現況と展望.第45回日本神経学会総会シンポジウム,遺伝性筋ジストロフィーの根本的治療をめざして.臨床神経,44: 911-913, 2004

島津美樹, 武田伸一: 筋ジストロフィーのモデル動物 ?「進化」する疾患モデル動物(第8回)?, 細胞工学,23: 1082-1085, 2004


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