Publication List befpre 2000

1. Ohashi, T, T. Yamamura, J-i. Inobe, T. Kondo, T. Kunishita, T. Tabira: Analysis of proteolipid protein (PLP)-specific T cells in multiple sclerosis: Identification of PLP 95-116 as an HLA-DR2,w15-associated determinant. Int Immunol 7:1771-1778, 1995
2. Kondo, T, T. Yamamura, J-i. Inobe, T. Ohashi, K. Takahashi, T. Tabira: TCR repertoire to proteolipid protein (PLP) in multiple sclerosis (MS). homologies between PLP-specific T cells and MS-associated T cells in TCR junctional sequences. Int Immunol 8:123-130, 1996
3. Kozovska, M, T. Yamamura, and T. Tabira. T-T cellular interaction between CD4-CD8- regulatory T cells and T cell clones presenting TCR peptide. Its implication for TCR vaccination against experimental autoimmune encephalomyelitis. J Immunol 157:1781-1790, 1996
4. Yamamura, T, T-C. Geng, M.F. Kozovska, K. Yokoyama, I.R. Cohen, T. Tabira: An α-chain TCR CDR3 peptide can enhance EAE induced by myelin basic protein or proteolipid protein. J Neurosci Res 45:706-713, 1996
5.Panchamoorthy G, Fukazawa T, Miyake S, Soltoff S, Reedquist K, Druker B, Shoelson S, Cantley L, Band H:p120cbl is major substrate of tyrosine phosphorylation upon B cell antigen receptor stimulation and interacts in vivo with Fyn and Syk tyrosine kinases, Grb2 and Shc adaptors, and the p85 subunit of Phosphatidylinositol 3-kinase. J Biol Chem 271:3187-3194, 1996
6.Miyake S*, Fukazawa T*, Band V, Band H:Tyrosine phosphorylation of Cbl upon epidermal growth factor (EGF) stimulation and its association with EGF receptor and downstream signaling proteins. J Biol Chem 271:14554-14559, 1996 * Eaqual contribution.
7.Lupher ML, Reedquist KA, Miyake S, Langdon WY Band H:A novel phosphotyrosine-binding domain in the N-terminal transforming region of Cbl interacts directly and selectively with ZAP-70 in T cells. J Biol Chem 271:24063-24068, 1996
8.Tokano Y, Miyake S, Kayagaki N, Nozawa K, Morimoto S, Azuma M, Yagita H, Takasaki Y, Okumura K, Hashimoto H:Soluble Fas molecule in the serum of patients with systemic lupus erythematosus. J Clin Immunol 16:261-265, 1996
9. Zhang, B-n, T. Yamamura, T. Kondo, M. Fujiwara, T. Tabira: Regulation of experimental autoimmune encephalomyelitis by natural killer (NK) cells. J Exp Med 186:1677-1687, 1997
10.Iai, M, T. Yamamura, S. Takashima: Early expression of proteolipid protein in human fetal and infantile cerebri. Pediat Neurol 17:235-239, 1997
11.Bonita D, Miyake S, Lupher ML, Langdon WY, Band H:Phophotyrosine binding domain-dependent upregulation of the platelet-derived growth factor receptor alpha singaling cascade by transforming mutants of Cbl:Implications for Cbl's function and oncogenicity. Mol Cell Biol 17:4597-4610, 1997
12.Zhang, B-n, T. Yamamura : The role of natural killer (NK) cells in experimental autoimmune encephalomyelitis. Proceedings for the 10th International Congress of Immunology 1089-1092, 1998
13.Miyake S, Lupher ML, Druker B, Band H:The tyrosine kinase regulator Cbl enhances the ubiquitination and degradation of the platelet derived growth factor receptor α. Proc Natl Acad Sci USA 95:7927-7932, 1998
14. Lupher ML, Rao N, Andoniou CE, Miyake S, Band H:Cbl-mediated negative regulation of the Syk tyrosine kinase: A critical role for Cbl PTB domain binding to Syk pY323. J Biol Chem 273:35273-35281, 1998
15.Illes, Z, T. Kondo, K. Yokoyama, T. Ohashi, T. Tabira, T. Yamamura: Identification of autoimmune T cells among in vivo expanded CD25+T cells in multiple sclerosis. J Immunol 162:1811-1817, 1999
16.Pal, E, T. Yamamura and T. Tabira: Autonomic regulation of experimental autoimmune encephalomyelitis in IL-4 knockout mice. J Neuroimmunol 100:149-155, 1999
17.Miyake S, Mullane KP, Douillard P, Band H:Cbl-mediated negative regulation of platelet-derived growth factor receptor-dependent cell proliferation. J Biol Chem 274:16619-16628, 1999
18.Illes, Z, T. Kondo, J. Newcombe, N. Oka, T. Tabira, and T. Yamamura: Differential expression of natural killer T cell Vα24J Q invariant TCR chain in the lesions of multiple sclerosis and chronic inflammatory demyelinating polyneuropathy. J Immunol 164:4375-4381, 2000
19.Kawamura, K, T. Yamamura, K. Yokoyama, D-H. Chui, Y. Fukui, T. Sasazuki, H. Inoko, C.S. David, and T. Tabira: HLA-DR2 restricted responses to proteolipid protein 95-116 peptide cause autoimmune encephalitis in transgenic mice. J Clin Invest 105:977-984, 2000
20.Lill NL, Douillard P, Awwad R, Ota S, Lupher ML, Miyake S, Meissner NS, Hsu V, Band H:The evolutionarily conserved N-terminal region of Cbl is sufficient to enhance down-regulation of the epidermal growth factor receptor. J Biol Chem 275:367-377, 2000
21.Rosenkranz S, Ikuno Y, Leong FL, Klinghoffer RA, Miyake S, Band H, Kazlauskas A. Src family kinases negatively regulate platelet-derived growth factor alpha receptor-dependent signaling and disease progression. J Biol Chem 275:9620-9627, 2000

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