• ホーム
  • 病院
  • 神経研究所
  • 精神保健研究所
  • TMCトランスレーショナル・メディカルセンター
  • メディカル・ゲノムセンター
  • 脳病態統合イメージングセンター
  • 認知行動療法センター
  • 災害時こころの情報支援センター

TOP ＞ メンバー一覧 ＞ メンバー　髙野　晴成

メンバー

髙野　晴成
Harumasa Takano, MD, PhD (Please go to the bottom for my English profile)

（研）国立精神・神経医療研究センター・脳病態統合イメージングセンター（IBIC）臨床脳画像研究部部長

医学博士、精神保健指定医、日本精神神経学会専門医・指導医、日本臨床精神神経薬理学会専門医・指導医、日本核医学会専門医、同・PET核医学認定医、Fellow, International Collegium of Neuropsychopharmacology

経歴

1994年 日本医科大学卒業、1996-2002年　慶應義塾大学医学部大学院神経精神医学専攻生
1994-2002年　国立精神・神経センター武蔵病院精神科研修医・レジデント、同・放射線診療部レジデントを経て精神科医員
2002-2006年　慶應義塾大学医学部精神神経科助手
2006-2011年　（独）放射線医学総合研究所分子イメージング研究センター研究員
2011-2014年　同・臨床研究支援室室長
2014年5月　国立精神・神経医療研究センター病院第一精神診療部医長
2017年10月より現職

研究業績（英文原著、最近3年間）

  1. Maekawa T, Sato N, Ota M, Sugiyama A, Sone D, Enokizono M, Kimura Y, Mukai Y, Murata M, Takano H, Imabayashi E, Matsuda H, Kunimatsu A, Abe O. Correlations between dopamine transporter density measured by 123I-FP-CIT SPECT and regional gray matter volume in Parkinson's disease. Jpn J Radiol. 2017 Oct 23;35(12):755-759
  2. Araki W, Hattori K, Kanemaru K, Yokoi Y, Omachi Y, Takano H, Sakata M, Yoshida S, Tsukamoto T, Murata M, Saito Y, Kunugi H, Goto YI, Nagaoka U, Nagao M, Komori T, Arima K, Ishii K, Murayama S, Matsuda H, Tachimori H, Araki YM, Mizusawa H. Re-evaluation of soluble APP-α and APP-β in cerebrospinal fluid as potential biomarkers for early diagnosis of dementia disorders. Biomark Res. 2017 Sep 22;5:28
  3. Moriguchi S, Takano H, Kimura Y, Nagashima T, Takahata K, Kubota M, Kitamura S, Ishii T, Ichise M, Zhang MR, Shimada H, Mimura M, Meyer JH, Higuchi M, Suhara T. Occupancy of Norepinephrine Transporter by Duloxetine in Human Brains Measured by Positron Emission Tomography with (S,S)-[18F]FMeNER-D2. Int J Neuropsychopharmacol. 2017 Dec 1;20(12):957-962
  4. Kubota M, Nagashima T, Takano H, Kodaka F, Fujiwara H, Takahata K, Moriguchi S, Kimura Y, Higuchi M, Okubo Y, Takahashi H, Ito H, Suhara T. Affinity States of Striatal Dopamine D2 Receptors in Antipsychotic-Free Patients with Schizophrenia. Int J Neuropsychopharmacol. 2017 Nov 1;20(11):928-935
  5. Kito S, Matsuda Y, Sewaki Y, Sekiya J, Fujii T, Noda T, Ikezawa S, Takano H, Nakazawa K, Nomura M, Setoyama S, Nakagome K. A 6-Month Follow-up Case Study of Low-Frequency Right Prefrontal Repetitive Transcranial Magnetic Stimulation in Treatment-Resistant Bipolar Depression. J ECT. 2017 Dec;33(4):e43-e44
  6. Sone D, Imabayashi E, Maikusa N, Okamura N, Furumoto S, Kudo Y, Ogawa M, Takano H, Yokoi Y, Sakata M, Tsukamoto T, Kato K, Matsuda H. Regional tau deposition and subregion atrophy of medial temporal structures in early Alzheimer's disease: A combined positron emission tomography/magnetic resonance imaging study. Alzheimers Dement (Amst). 2017 Aug 4;9:35-40
  7. Ito H, Kawaguchi H, Kodaka F, Takuwa H, Ikoma Y, Shimada H, Kimura Y, Seki C, Kubo H, Ishii S, Takano H, Suhara T. Normative data of dopaminergic neurotransmission functions in substantia nigra measured with MRI and PET: Neuromelanin, dopamine synthesis, dopamine transporters, and dopamine D2 receptors. Neuroimage. 2017 Jun 26;158:12-17
  8. Takano H, Ito S, Zhang X, Ito H, Zhang MR, Suzuki H, Maeda K, Kusuhara H, Suhara T, Sugiyama Y. Possible Role of Organic Cation Transporters in the Distribution of [11C]Sulpiride, a Dopamine D2 Receptor Antagonist. J Pharm Sci. 2017 May 10;106(9):2558-2565
  9. Narita Z, Takano H, Sumiyoshi T. Successful treatment for psychomotor agitation in neuromyelitis optica spectrum disorder with trazodone-risperidone combination: a case report. Neuropsychiatr Dis Treat. 2017 Mar 13;13:775-777
  10. Moriguchi S, Kimura Y, Ichise M, Arakawa R, Takano H, Seki C, Ikoma Y, Takahata K, Nagashima T, Yamada M, Mimura M, Suhara T. PET Quantification of the Norepinephrine Transporter in Human Brain with (S,S)-18F-FMeNER-D2. J Nucl Med. 2016 Dec 15;58(7):1140-1145
  11. Moriguchi S, Yamada M, Takano H, Nagashima T, Takahata K, Yokokawa K, Ito T, Ishii T, Kimura Y, Zhang MR, Mimura M, Suhara T. Norepinephrine Transporter in Major Depressive Disorder: A PET Study. Am J Psychiatry. 2016 Sep 15;174(1):36-41
  12. Kimura Y, Ichise M, Ito H, Shimada H, Ikoma Y, Seki C, Takano H, Kitamura S, Shinotoh H, Kawamura K, Zhang MR, Sahara N, Suhara T, Higuchi M. PET Quantification of Tau Pathology in Human Brain with 11C-PBB3. J Nucl Med.　2015 Jul 16;56(9):1359-65
  13. Takano H, Arakawa R, Nogami T, Suzuki M, Nagashima T, Fujiwara H, Kimura Y, Kodaka F, Takahata K, Shimada H, Murakami Y, Tateno A, Yamada M, Ito H, Kawamura K, Zhang M, Takahashi H, Kato M, Okubo Y, Suhara T. Norepinephrine transporter occupancy by nortriptyline in patients with depression: a positron emission tomography study with (S,S)-[18F]FMeNER-D2. Int J Neuropsychopharmacol. 2014 Apr;17(4):553-60
  14. Takano H, Ito H, Takahashi H, Arakawa R, Okumura M, Kodaka F, Otsuka T, Kato M, Suhara T. Serotonergic neurotransmission in the living human brain: A positron emission tomography study using [11C]DASB and [11C]WAY100635 in young healthy men. Synapse. 2011;65(7):624-633.
  15. Takano H, Motohashi N, Uema T, Ogawa K, Ohnishi T, Nishikawa M, Mastuda H. Differences in cerebral blood flow between missed and generalized seizures with electroconvulsive therapy: A positron emission tomographic study. Epilepsy Res. 2011;97(1-2):225-8.
  16. Takano H, Motohashi N, Uema T, Ogawa K, Ohnishi T, Nishikawa M, Kashima H, Matsuda H. Changes in regional cerebral blood flow during acute electroconvulsive therapy in patients with depression: Positron emission tomographic study. Br J Psychiatry. 2007;190(1):63-68.

English profile


Harumasa Takano, MD, PhD
Director, Department of Clinical Neuroimaging, Integrative Brain Imaging Center (IBIC)National Center of Neurology and Psychiatry (NCNP)
Address: Ogawahigashi-cho 4-1-1, Kodaira 187-8551, Tokyo, Japan
Phone: +81-42-341-2711
Email: hrtakano[at]ncnp.go.jp

My research interests include brain imaging for neuropsychiatric disorders (mood disorders, schizophrenia, and neurocognitive disorders) using positron emission tomography (PET) and magnetic resonance imaging (MRI).

Publications (Original articles in the last 3 years)
Please see above