NCNP Biobank

NCNP Biobank

NCNP Biobank

Features of NCNP Biobank

Bioresources for developing the next generation diagnosis and treatment of neuropsychiatric and muscular diseases

Features of NCNP Biobank

Introduction of NCNP

Located in the west metropolitan area of Tokyo. One hospital and two research institutes are working together to investigate the cause of neuropsychiatric diseases yet to be elucidated, to establish the treatment method, and to develop a model medical care.

National Center Biobank Project

National Center Biobank Project

Six national centers in Japan collaborate to form the National Center Biobank Network(NCBN), where we are standardizing collection methods and data format, and establishing a large database which researchers can access.

Sample and data collection flow

Sample and data collection flow

For the patients, joining to the biobank would enrich the information that can contribute the clinical practice

Available Samples

Registered Samples(As of 2018/03/31)
Diseases Patients Cerebro-spinal Plasma Serum DNA DNA
(pre-extracted)
Pathological
Tissues
Frozen
Muscles
Schizophrenia 401 51 414 220 362 403 0 0
Major Depressive Disorder 318 92 298 183 276 290 0 0
Bipolar Disorder 217 38 252 144 240 244 0 0
Controls 1,098 0 282 158 1,111 266 0 0
Developemental Disorder 354 27 90 66 345 86 1 0
Epilepsy 596 393 118 62 423 94 28 0
Parkinson Disease 291 315 207 138 189 207 0 0
Arzheimer-type Dementia 174 45 159 96 138 159 0 0
Mild Dementia 209 29 199 182 196 199 0 0
Other Dementia 290 108 264 216 245 258 0 0
MultipleSclrosis (inc. NMO) 554 831 504 276 495 484 0 0
Muscle Diseases 10,176 18 8 7 1,417 7 0 10,145
Others 1,662 1,525 732 502 1,003 729 1 0
Subtotal 15,986 3,302 3,380 2,142 6,222 3,284 29 10,145
Total 28,504

The table above indicate the number of participants joined and donated their samples (plasma and DNA) in the standardized methods according to the National Center Biobank Project. We also have 14000 muscular tissues, 1000 CSFs and 250 brain samples collected by ordinary method.

Access and use

Available Samples

A research plan submitted to Biobank secretariat will reviewed
by both utilization committee and joint-research committee.
※For academic use (Contact us directly in the case of industrial use)

Database

Database

We developed an database (DB) system for the sample and information management. Our DB has reciprocal data flow with hospital information system and can export the data to research datawarehouse and central DB of 6NCBB.

Approved research

User Sample Analyses
A: National research centerPlasma Metabolome
B: National University Plasma Metabolome
C: Research Institute Plasma Amino acid
D: University DNA Sequencing
E: University Plasma ELISA
F: University DNA Methylation

Contact

NCNP Biobank secretariat

biobank@ncnp.go.jp

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