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国立研究開発法人 国立精神・神経医療研究センター   ・English  ・Japanese

スタッフstaff

心身症研究室 室長

関口 敦(SEKIGUCHI Atsushi, MD, Ph.D.)

博士(医学)


活動紹介・略歴

東北大学医学部卒業(2000年)。山形市立病院済生館・内科研修医(2000年~2002年)、九州大学心療内科・研究生(2002年~2003年)、国立精神・神経センター 国府台病院・心療内科レジデント(2003年~2005年)、東北大学医学系研究科 博士課程修了(医学博士)(2005年~2009年)、東北大学 加齢医学研究所・博士研究員(2009年~2012年)、同・助教(2012年)、東北大学 東北メディカル・メガバンク機構 講師(2012年~2015年)、同・准教授(2015年)。2015年10月より、国立精神・神経医療研究センター 精神保健研究所 成人精神保健研究部 精神機能研究室長に着任、(併任)東北大学 非常勤講師


研究テーマ

心理社会的ストレスに関わる脳活動、脳形態変化
ストレス関連疾患のバイオマーカー検索


受賞歴

2015年:東北大学 医学部奨学賞 銀賞
2013年:東北大学研究所連携プロジェクト若手研究者賞
2012年:第11回日本トラウマティック・ストレス学会奨励賞
2012年:American Psychosomatic Society Young Scholar Award
2011年:American Psychosomatic Society Travel Award for MacLean Scholars


主要論文

【英文原著】

Nakagawa S, Takeuchi H, Taki Y, Nouchi R, Sekiguchi A, Kotozaki Y, Miyauchi CM, Iizuka K, Yokoyama R, Shinada T, Yamamoto Y, Hanawa S, Araki T, Hashizume H, Kunitoki K, Sassa Y, Kawashima R: The anterior midcingulate cortex as a neural node underlying hostility in young adults. Brain Structure and Function, 222(1): 61-70, 2017.

Takeuchi H, Taki Y, Nouchi R, Yokoyama R, Kotozaki Y, Nakagawa S, Sekiguchi A, Iizuka K, Yamamoto Y, Hanawa S, Araki T, Miyauchi CM, Shinada T, Sakaki K, Sassa Y, Nozawa T, Ikeda S, Yokota S, Daniele M, Kawashima R: Creative females have larger white matter structures: evidence from a large sample study. Human Brain Mapping, 38(1): 414-430. 2017.

Takeuchi H, Taki Y, Sekiguchi A, Nouchi R, Kotozaki Y, Nakagawa S, Miyauchi CM, Iizuka K, Yokoyama R, Shinada T, Yamamoto Y, Hanawa S, Araki T, Kunitoki K, Sassa Y, Kawashima R: Mean diffusivity of basal ganglia and thalamus specifically associated with motivational states among mood states. Brain Structure and Function, 222(2): 1027-1037, 2017.

Takeuchi H, Taki Y, Nouchi R, Yokoyama R, Kotozaki Y, Nakagawa S, Sekiguchi A, Iizuka K, Yamamoto Y, Hanawa S, Araki T, Miyauchi CM, Shinada T, Sakaki K, Nozawa T, Ikeda S, Yokota S, Magistro D, Sassa Y, Kawashima R: Regional homogeneity, resting-state functional connectivity and amplitude of low frequency fluctuation associated with creativity measured by divergent thinking in a sex-specific manner. Neuroimage, Volume 152, 258–269, 2017.

Takeuchi H, Taki Y, Nouchi R, Sekiguchi A, Kotozaki Y, Nakagawa S, Miyauchi CM, Sassa Y, Kawashima R: Neural plasticity in amplitude of low frequency fluctuation, cortical hub construction, regional homogeneity resulting from working memory training. Scientific Reports, May 3; 7(1): 1470, 2017.

Tatewaki Y, Mutoh T, Benjamin T, Omodaka K, Murata T, Sekiguchi A, Nakazawa T, Taki Y: Phase Difference-Enhanced Magnetic Resonance (MR) Imaging (PADRE) Technique for the Detection of Age-Related Microstructural Changes in Optic Radiation: Comparison with Diffusion Tensor Imaging (DTI). Medical Science Monitor 23: 5495-5503. 2017.

Nakagawa S, Takeuchi H, Taki Y, Nouchi R, Kotozaki Y, Shinada T, Maruyama T, Sekiguchi A, Iizuka K, Yokoyama R, Yamamoto Y, Hanawa S, Araki T, Miyauchi CM, Magistro D, Sakaki K, Jeong H, Sasaki Y, Kawashima R: Lenticular nucleus correlates of general self-efficacy in young adults. Brain Structure and Function 222(7): 3309–3318.

Takeuchi H, Tomita H, Taki Y, Kikuchi Y, Ono C, Yu Z, Sekiguchi A, Nouchi R, Kotozaki Y, Nakagawa S, Miyauchi CM, Iizuka K, Yokoyama R, Shinada T, Yamamoto Y, Hanawa S, Araki T, Kunitoki K, Sassa Y, Kawashima R: The VEGF gene polymorphism impacts brain volume and arterial blood volume. Human Brain Mapping 38(7): 3516-3526.

Sekiguchi A*, Sato C*, Matsudaira I, Kotozaki Y, Nouchi R, Takeuchi H, Kawai M, Tada H, Ishida T, Taki Y, Ohuchi N, Kawashima R: Postoperative hormonal therapy prevents recovery of neurological damage after surgery in patients with breast cancer. Scientific Reports, Oct 6; 6: 34671, 2016. (*equal contribution)

Nakagawa S, Sugiura M, Sekiguchi A, Kotozaki Y, Miyauchi CM, Hanawa S, Araki T, Takeuchi H, Sakuma A, Taki Y, Kawashima R: Effects of post-traumatic growth on the dorsolateral prefrontal cortex after a disaster. Scientific Reports, Sep 27; 6: 34364, 2016.

Nouchi R, Takeuchi H, Taki Y, Sekiguchi A, Kotozaki Y, Nakagawa S, Miyauchi CM, Iizuka K, Yokoyama R, Shinada T, Yamamoto Y, Hanawa S, Araki T, Sassa Y, Kawashima R: Neuroanatomical bases of effortful control: evidence from a large sample of young healthy adults using voxel-based morphometry. Scientific Reports, 631231, 2016.

Nakagawa S, Takeuchi H, Taki Y, Nouchi R, Sekiguchi A, Kotozaki Y, Miyauchi CM, Iizuka K, Yokoyama R, Shinada T, Yamamoto Y, Hanawa S, Araki T, Kunitoki K, Sassa Y, Kawashima R: Sex-related differences in the effects of sleep habits on verbal and visuospatial working memory. Frontiers in Psychology, 7: 1128, 2016.

Takeuchi H, Taki Y, Sekiguchi A, Nouchi R, Kotozaki Y, Nakagawa S, Miyauchi CM, Iizuka K, Yokoyama R, Shinada T, Yamamoto Y, Hanawa S, Araki T, Hashizume H, Kunitoki K, Sassa Y, Kawashima R: Differences in gray matter structure correlated to nationalism and patriotism. Scientific Reports, 15; 6: 29912. 2016.

Akimoto Y, Nozawa T, Kanno A, Kambara T, Ihara M, Ogawa T, Goto T, Taki Y, Yokoyama R, Kotozaki Y, Nouchi R, Sekiguchi A, Takeuchi H, Miyauchi CM, Sugiura M, Okumura E, Sunda T, Shimizu T, Tozuka E, Hirose S, Nanbu T, Kawashima R: High-gamma power changes after cognitive intervention: preliminary results from twenty-one senior adult subjects. Brain and Behavior, 6(3): e00427, 2016.

Nouchi R, Taki Y, Takeuchi H, Nozawa T, Sekiguchi A, Kawashima R: Reading aloud and solving simple arithmetic calculation intervention (Learning therapy) improves inhibition, verbal episodic memory, focus attention, and processing speed in healthy elderly people: Evidence from a randomized controlled trial. Frontiers in Human Neuroscience, 10: 217, 2016.

Nakagawa S, Takeuchi H, Taki Y, Nouchi R, Kotozaki Y, Shinada T, Maruyama T, Sekiguchi A, Iizuka K, Yokoyama R, Yamamoto Y, Hanawa S, Araki T, Miyauchi CM, Magistro D, Sakaki K, Jeong H, Sasaki Y, Kawashima R: Basal ganglia correlates of fatigue in young adults. Scientific Reports, 19; 6: 21386. 2016.

Sato C*, Sekiguchi A*, Kawai M, Kotozaki Y, Nouchi R, Tada H, Takeuchi H, Ishida T, Taki Y, Kawashima R, Ohuchi N: Postoperative structural brain changes and cognitive dysfunction in patients with breast cancer. PLoS ONE, 10(11): e0140655, 2015 (* equal contribution)

Sekiguchi A, Kotozaki Y, Sugiura M, Nouchi R, Takeuchi H, Hanawa S, Nakagawa S , Miyauch CM, Araki T, Sakuma A, Taki Y, Kawashima R: Resilience after 3/11: Structural brain changes 1 year after the Japanese Earthquake. Molecular Psychiatry, (20), 553–554, 2015.

Nakagawa S, Takeuchi H, Taki Y, Nouchi R, Sekiguchi A, Kotozaki Y, Miyauchi CM, Iizuka K, Yokoyama R, Shinada T, Yamamoto Y, Hanawa S, Araki T, Hashizume H, Kunitoki K, Sassa Y, Kawashima R: White matter structures associated with loneliness in young adults. Scientific Reports, 20; 5: 17001, 2015.

Takeuchi H, Taki Y, Sekiguchi A, Nouchi R, Kotozaki Y, Nakagawa S, Miyauchi CM, Iizuka K, Yokoyama R, Shinada T, Yamamoto Y, Hanawa S, Araki T, Hashizume H, Kunitoki K, Sassa Y, Kawashima R: Amygdala and cingulate structure is associated with stereotype on sex-role. Scientific Reports, 5: 14220, 2015.

Magistro D, Takeuchi H, Kashkouli Nejad K, Taki Y, Sekiguchi A, Nouchi R, Kotozaki Y, Nakagawa S, Miyauchi CM, Iizuka K, Yokoyama R, Shinada T, Yamamoto Y, Hanawa S, Araki T, Hashizume H, Sassa Y, Kawashima R: The relationship between processing speed and regional white matter volume in healthy young people. PLoS ONE, 10(9): e0136386, 2015.

Takeuchi H, Taki Y, Nouchi R, Sekiguchi A, Hashizume H, Sassa Y, Kotozaki Y, Miyauchi CM, Yokoyama R, Iizuka K, Nakagawa S, Nagase T, Kunitoki K, Kawashima R: Degree centrality and fractional amplitude of low-frequency oscillations associated with Stroop interference. Neuroimage, 119: 197-209, 2015.

Takeuchi H, Tomita H, Taki Y, Kikuchi Y, Ono C, Yu Z, Sekiguchi A, Nouchi R, Kotozaki Y, Nakagawa S, Miyauchi CM, Iizuka K, Yokoyama R, Shinada T, Yamamoto Y, Hanawa S, Araki T, Hashizume H, Kunitoki K, Sassa Y, Kawashima R: The associations among the dopamine D2 receptor Taq1, emotional intelligence, creative potential measured by divergent thinking, and motivational state and these associations’ sex differences. Frontiers in Psychology, 6: 912, 2015.

Takeuchi H, Taki Y, Sassa Y, Sekiguchi A, Nagase T, Nouchi R, Fukushima A, Kawashima R: The associations between regional gray matter structural changes and changes of cognitive performance in control groups of intervention studies. Frontiers in Human Neuroscience, 9: 681, 2015.

Takeuchi H, Taki Y, Sekiguchi A, Nouchi R, Kotozaki Y, Nakagawa S, Miyauchi CM, Iizuka K, Yokoyama R, Shinada T, Yamamoto Y, Hanawa S, Araki T, Kunitoki K, Sassa Y, Kawashima R: Regional gray matter density is associated with morningness–eveningness: evidence from voxel-based morphometry. Neuroimage, 117: 294-304, 2015.

Hashimoto T, Takeuchi H, Taki Y, Sekiguchi A, Nouchi R, Kotozaki Y, Nakagawa S, Miyauchi CM, Ikuza K, Yokoyama R, Shinada T, Yamamoto Y, Hanawa S, Araki T, Hashizume H, Kunitoki K, Kawashima R: Neuroanatomical correlates of the sense of control: Gray and white matter volumes associated with an internal locus of control. Neuroimage, 119: 146-151, 2015.

Takeuchi H, Taki Y, Nouchi R, Hashizume H, Sekiguchi A, Kotozaki Y, Nakagawa S, Miyauchi CM, Sassa Y, Kawashima R: Working memory training impacts the mean diffusivity in the dopaminergic system. Brain Structure and Function, 220(6): 3101-11, 2015.

Nozawa T, Taki Y, Kanno A, Akimoto Y, Ihara M, Yokoyama R, Kotozaki Y, Nouchi R, Sekiguchi A, Takeuchi H, Miyauchi CM, Ogawa T, Goto T, Sunda T, Shimizu T, Tozuka E, Hirose S, Nanbu T, Kawashima R: Effects of different types of cognitive training on cognitive function, brain structure, and driving safety in senior daily drivers: A pilot study. Behavioural Neurology, 2015: 525901, 2015.

Takeuchi H, Taki Y, Sekiguchi A, Nouchi R, Kotozaki Y, Nakagawa S, Miyauchi CM, Iizuka K, Yokoyama R, Shinada T, Yamamoto Y, Hanawa S, Araki T, Hashizume H, Sassa Y, Kawashima R: Brain structures in the sciences and humanities. Brain Structure and Function, 220(6): 3295-305, 2015.

Takeuchi H, Tomita H, Taki Y, Kikuchi Y, Ono C, Yu Z, Sekiguchi A, Nouchi R, Kotozaki Y, Nakagawa S, Miyauchi CM, Iizuka K, Yokoyama R, Shinada T, Yamamoto Y, Hanawa S, Araki T, Hashizume H, Kunitoki K, Sassa Y, Kawashima R: Cognitive and neural correlates of the 5-repeat allele of the dopamine D4 receptor gene in a population lacking the 7-repeat allele. Neuroimage, 15; 110: 124-35, 2015.

Yokoyama R, Nozawa T, Takeuchi H, Taki Y, Sekiguchi A, Nouchi R, Kotozaki Y, Nakagawa S, Miyauchi CM, Iizuka K, Shinada T, Yamamoto Y, Hanawa S, Araki T, Hashizume H, Kunitoki K, Hanihara M, Sassa Y, Kawashima R: Regional Gray Matter Density Associated with Cognitive Reflectivity–Impulsivity: Evidence from Voxel-Based Morphometry. PLoS ONE 24; 10(3): e0122666, 2015.

Takeuchi H, Taki Y, Sekiguchi A, Hashizume H, Nouchi R, Sassa Y, Kotozaki Y, Miyauchi CM, Yokoyama R, Iizuka K, Nakagawa S, Nagase T, Kunitoki K, Kawashima R: Mean diffusivity of globus pallidus associated with verbal creativity measured by divergent thinking and creativity-related temperaments in young healthy adults. Human Brain Mapping, 36(5): 1808-27, 2015.

Takeuchi H, Taki Y, Nouchi R, Hashizume H, Sekiguchi A, Kotozaki Y, Nakagawa S, Miyauchi CM, Sassa Y, Kawashima R: The structure of the amygdala associates with human sexual permissiveness: evidence from voxel-based morphometry. Human Brain Mapping, 36(2): 440-8, 2015.

Nakagawa S, Takeuchi H, Taki Y, Nouchi R, Sekiguchi A, Kotozaki Y, Miyauchi CM, Iizuka K, Yokoyama R, Shinada T, Yamamoto Y, Hanawa S, Araki T, Hashizume H, Kunitoki K, Sassa Y, Kawashima R: Comprehensive neural networks for guilty feelings in young adults. NeuroImage, 105: 248-56, 2015.

Sekiguchi A, Kotozaki Y, Sugiura M, Nouchi R, Takeuchi H, Hanawa S, Nakagawa S, Miyauchi CM, Araki T, Sakuma A, Taki Y, Kawashima R: Long-term effects of post-earthquake distress on brain microstructural changes. BioMed Research International, 2014, 180468, 2014.

Sekiguchi A, Sugiura M, Taki Y, Kotozaki Y, Nouchi R, Takeuchi H, Araki T, Hanawa S, Nakagawa S, Miyauchi CM, Sakuma A, Kawashima R: White matter microstructural changes as vulnerability factors and acquired signs of post-earthquake distress. PLoS ONE, 9(1): e83967, 2014.

Takeuchi H, Taki Y, Sekiguchi A, Nouchi R, Kotozaki Y, Nakagawa S, Miyauchi CM, Iizuka K, Yokoyama R, Shinada T, Yamamoto Y, Hanawa S, Araki T, Hashizume H, Sassa Y, Kawashima R: Creativity measured by divergent thinking is associated with two axes of autistic characteristics. Frontiers in Psychology, 5: 921, 2014.

Takeuchi H, Taki Y, Sekiguchi A, Nouchi R, Kotozaki Y, Nakagawa S, Miyauchi CM, Iizuka K, Yokoyama R, Shinada T, Yamamoto Y, Hanawa S, Araki T, Hashizume H, Sassa Y, Kawashima R: Creativity measured by divergent thinking is associated with two axes of autistic characteristics. Frontiers in Psychology, 5: 921, 2014.

Nakagawa S, Sugiura M, Sekiguchi A, Kotozaki Y, Araki T, Hanawa S, Miyauchi CM, Sakuma A, Kawashima R: Fatigue and relating to others 3 months after the 2011 Great East Japan Earthquake. Psychiatric Research, 218(3): 324-8, 2014.

Kotozaki Y, Takeuchi H, Sekiguchi A, Yamamoto Y, Shinada T, Araki T, Takahashi K, Taki Y, Ogino T, Kiguchi M, Kawahima R: Biofeedback-based training for stress management in daily hassles: An intervention study. Brain and Behavior, 4(4): 566-79, 2014.

Takeuchi H, Taki Y, Nouchi R, Sekiguchi A, Hashizume H, Sassa Y, Kotozaki Y, Miyauchi CM, Yokoyama R, Iizuka K, Nakagawa S, Nagase T, Kunitoki K, Kawashima R: Association between resting-state functional connectivity and empathizing/systemizing. Neuroimage, 99: 312-22. 2014.

Takeuchi H, Taki Y, Nouchi R, Sekiguchi A, Hashizume H, Sassa Y, Kotozaki Y, Miyauchi CM, Yokoyama R, Iizuka K, Nakagawa S, Nagase T, Kunitoki K, Kawashima R: Association between resting-state functional connectivity and empathizing/systemizing. Neuroimage, 99: 312-22. 2014.

Takeuchi H, Taki Y, Nouchi R, Hashizume H, Sassa Y, Sekiguchi A, Kotozaki Y, Nakagawa S, Nagase T, Miyauchi CM, Kawashima R: Anatomical correlates of quality of life: Evidence from voxel-based morphometry. Human Brain Mapping, 35(5): 1834-46, 2014.

Sugiura M, Yomogida Y, Mano Y, Sassa Y, Toshimune K, Sekiguchi A, Kawashima R: From social-signal detection to higher social cognition: an fMRI approach. Social Cognitive and Affective Neuroscience, 9(9):1303-9, 2014.

Nouchi R, Taki Y, Takeuchi H, Sekiguchi A, Hashizume H, Nozawa T, Nouchi H, Kawashima R: Four weeks combination exercise training improved executive functions, episodic memory and processing speed in healthy elderly people: Evidence from a randomized controlled trial. AGE, 36(2), 787–799, 2014.

Yokoyama R, Nozawa T, Takeuchi H, Taki Y, Sekiguchi A, Nouchi R, Kotozaki Y, Nakagawa S, Miyauchi CM, Iizuka K, Shinada T, Yamamoto Y, Hanawa S, Araki T, Hashizume H, Kunitoki K, Hanihara M, Sassa Y, Kawashima R: Association between gray matter volume in the caudate nucleus and financial extravagance: findings from voxel-based morphometry. Neuroscience Letters, Jan 28; 563C: 28-32, 2014.

Takeuchi H, Taki Y, Nouchi R, Sekiguchi A, Kotozaki Y, Miyauchi CM, Yokoyama R, Iizuka K, Hashizume H, Nakagawa S, Kunitoki K, Sassa Y, Kawashima R: Regional gray matter density is associated with achievement motivation: evidence from voxel-based morphometry. Brain Structure and Function, Jan; 219(1): 71-83. 2014.

Takeuchi H, Taki Y, Sassa Y, Hashizume H, Sekiguchi A, Fukushima A, Kawashima R: Regional gray matter volume is associated with empathizing and systemizing in young adults. PLoS ONE, 9(1): e84782, 2014.

Takeuchi H, Taki Y, Nouchi R, Hashizume H, Sassa Y, Sekiguchi A, Kotozaki Y, Nakagwa S, Nagase T, Miyauch MC, Kawashima R: Associations among imaging measures (2): The association between gray matter concentration and task-induced activation changes. Human Brain Mapping, Jan; 35(1): 185-98, 2014.

Sekiguchi A, Sugiura M, Taki Y, Kotozaki Y, Nouchi R, Takeuchi H, Araki T, Hanawa S, Nakagawa S, Miyauchi CM, Sakuma A, Kawashima R: Brain structural changes as vulnerability factors and acquired signs of post-earthquake stress. Molecular Psychiatry, Vol 18, 618-623, 2013.

Sekiguchi A, Sugiura M, Yokoyama S, Sassa Y, Horie K, Sato S, Kawashima R: Neural correlates of adaptive social responses to real-life frustrating situations: a functional MRI study. BMC neuroscinece, 14: 29, 2013.

Kotozaki Y, Takeuchi H, Sekiguchi A, Araki T, Yamamoto Y, Takahashi K, Nozawa T, Taki Y, Shinada T, Sugiura M, Tomita H, Kawashima R: Psychological Effects of the Great East Japan Earthquake: Posttraumatic Stress, Psychological Effects and the Cortisol Levels in Women Who Live in the Coastal Disaster Areas. Human Science & Technology, Vol. 10, 2012, 38-45, 2013.

Takeuchi H, Taki Y, Sekiguchi A, Nouchi R, Kotozaki Y, Nakagawa S, Miyauchi CM, Iizuka K, Yokoyama R, Shinada T, Yamamoto Y, Hanawa S, Araki T, Hashizume H, Kunitoki K, Sassa Y, Kawashima R: Association of hair iron levels with creativity and psychological variables related to creativity. Frontiers in Human Neuroscience, 18; 7: 875, 2013.

Nouchi R, Taki Y, Takeuchi H, Hashizume H, Nozawa T, Kambara T, Sekiguchi A, Miyauchi CM, Kotozaki Y, Nouchi H, Kawashima R: Brain training game boosts executive functions, working memory and processing speed in the young adults: A randomized controlled trial. PLoS ONE, 8(2): e55518, 2013.

Nouchi R, Taki Y, Takeuchi H, Hashizume H, Nozawa T, Kambara T, Sekiguchi A, Miyauchi CM, Kotozaki Y, Nouchi H, Kawashima R: Brain training game boosts executive functions, working memory and processing speed in the young adults: A randomized controlled trial. PLoS ONE, 8(2): e55518, 2013.

Takeuchi H, Taki Y, Nouchi R, Hashizume H, Sekiguchi A, Kotozaki Y, Nakagawa S, Miyauchi CM, Sassa Y, Kawashima R: Effects of working memory-training on functional connectivity and cerebral blood flow during rest. Cortex Sep; 49(8): 2106-25, 2013.

Takeuchi H, Taki Y, Thyreau B, Sassa Y, Hashizume H, Sekiguchi A, Nagase T, Nouchi R, Fukushima A, Kawashima R: White matter structures associated with empathizing and systemizing in young adults. Neuroimage, Aug 15;77: 222-36, 2013.

Takeuchi H, Taki Y, Nouchi R, Sekiguchi A, Hashizume H, Sassa Y, Kotozaki Y, Miyauchi CM, Yokoyama R, Iizuka K, Nakagawa S, Nagase T, Kunitoki K, Kawashima R: Resting state functional connectivity associated with trait emotional intelligence. Neuroimage Jun 21; 83C: 318-328, 2013.

Takeuchi H, Taki Y, Sassa Y, Hashizume H, Sekiguchi A, Nagase T, Nouchi R, Fukushima A, Kawashima R: White matter structures associated with emotional intelligence: evidence from diffusion tensor imaging. Human Brain Mapping, May; 34(5): 1025-34, 2013.

Takeuchi H, Taki Y, Nouchi R, Hashizume H, Sekiguchi A, Kotozaki Y, Nakagawa S, Miyauchi CM, Sassa Y, Kawashima R: Anatomical correlates of self-handicapping tendency. Cortex, Apr; 49(4): 1148-54, 2013.

Takeuchi H, Taki Y, Sassa Y, Hashizume H, Sekiguchi A, Fukushima A, Kawashima R. "Brain structures associated with executive functions during everyday events in a non-clinical sample. Brain Structure & Function, Jul; 218(4): 1017-32, 2013.

Takeuchi H, Taki Y, Nouchi R, Sekiguchi A, Kotozaki Y, Miyauchi CM, Yokoyama R, Iizuka K, Hashizume H, Nakagawa S, Kunitoki K, Sassa Y, Kawashima R: A voxel-based morphometry study of gray and white matter correlates of a need for uniqueness. Neuroimage, 63(3): 1119-1126, 2012.

Nouchi R, Taki Y, Takeuchi H, Hashizume H, Nozawa T, Sekiguchi A, Nouchi H, Kawashima R: Beneficial effects of short-term combination exercise training on diverse cognitive functions in healthy elderly people: Study protocol for a randomized controlled trial. Trials, 13: 200, 2012.

Nouchi R, Taki Y, Takeuchi H, Hashizume H, Nozawa T, Sekiguchi A, Nouchi H, Kawashima R: Beneficial effects of reading aloud and solving simple arithmetic calculations (Learning therapy) on a wide range of cognitive functions in the healthy elderly: Study protocol for a randomized controlled trial. Trials, 13: 32, 2012.

Takeuchi H, Sugiura M, Sassa Y, Sekiguchi A, Yomogida Y, Taki Y, Kawashima R: Neural correlates of the difference between working memory speed and simple sensorimotor speed: an fMRI study. PLoS ONE, 7(1): e30579, 2012.

Nouchi R, Taki Y, Takeuchi H, Hashizume H, Akitsuki Y, Shigemune Y, Sekiguchi A, Kotozaki Y, Tsukiura T, Yomogida Y, Kawashima R: Brain training game improves executive functions and processing speed in the elderly. PLoS ONE, 7(1): e29676, 2012.

Takeuchi H, Taki Y, Sassa Y, Hashizume H, Sekiguchi A, Nagase T, Nouchi R, Fukushima A, Kawashima R: Regional gray and white matter volume associated with Stroop interference: Evidence from voxel-based morphometry. NeuroImage, 59: 2899-2907, 2012.

Oikawa H, Sugiura M, Sekiguchi A, Tsukiura T, Miyauchi CM, Hashimoto T, Takano-Yamamoto T, Kawashima R: Self-face evaluation and self-esteem in young females : an fMRI study using contrast effect. NeuroImage, 59: 3668-3676, 2012.

Sekiguchi A, Yokoyama S, Kasahara S, Yomogida Y, Takeuchi H, Ogawa T, Taki Y, Niwa SI, Kawashima R: Neural bases of a specific strategy for visuospatial processing in rugby players. Medicine & Science in Sports & Exercise, 43 (10): 1857-1862, 2011.

Takeuchi H, Taki Y, Sassa Y, Hashizume H, Sekiguchi A, Fukushima A, Kawashima R: Verbal working memory performance correlates with regional white matter structures in the frontoparietal regions. Neuropsychologia, 49, 3466-3473, 2011.

Takeuchi H, Taki Y, Sassa Y, Hashizume H, Sekiguchi A, Fukushima A, Kawashima R: Working memory training using mental calculation impacts regional gray matter of the frontal and parietal regions. PLoS ONE, 6(8): e23175, 2011.

Mano Y, Sugiura M, Tsukiura T, Chiao JY, Yomogida Y, Jeong H, Sekiguchi A, Kawashima R: The representation of social interaction in episodic memory: a functional MRI study. NeuroImage, 57: 1234-1242, 2011.

Takeuchi H, Taki Y, Sassa Y, Hashizume H, Sekiguchi A, Fukushima A, Kawashima R: Regional gray matter density associated with emotional intelligence: evidence from voxel-based morphometry. Human Brain Mapping, 32: 1497-1510, 2011.

Tsukiura T, Sekiguchi A, Yomogida Y, Nakagawa S, Shigemune Y, Kambara T, Akitsuki Y, Taki Y, Kawashima R: Effects of aging on hippocampal and anterior temporal activations during successful retrieval of memory for face-name associations. Journal of Cognitive Neuroscience, 23: 200-213, 2011.

Tsukiura T, Mano Y, Sekiguchi A, Yomogida Y, Hoshi K, Kambara T, Takeuchi H, Sugiura M, Kawashima R: Dissociable roles of the anterior temporal regions in successful encoding of memory for person identity information. Journal of Cognitive Neuroscience, 22: 2226-2237, 2010.

Takeuchi H, Taki Y, Sassa Y, Hashizume H, Sekiguchi A, Fukushima A, Kawashima R: Regional gray matter volume of dopaminergic system associate with creativity: evidence from voxel-based morphometry. NeuroImage, 51: 578-585, 2010.

Takeuchi H, Taki Y, Sassa Y, Hashizume H, Sekiguchi A, Fukushima A, Kawashima R: White matter structures associated with creativity: evidence from diffusion tensor imaging. NeuroImage, 51: 11-18, 2010.

Takeuchi H, Sekiguchi A, Taki Y, Yokoyama S, Yomogida Y, Komuro N, Yamanouchi T, Suzuki S, Kawashima R: Training of working memory impacts structural connectivity. Journal of Neuroscience, 30: 3297-303, 2010.

Yomogida Y, Sugiura M, Sassa Y, Wakusawa K, Sekiguchi A, Fukushima A, Takeuchi H, Horie K, Sato S, Kawashima R: The Neural Basis of Agency: An fMRI study. NeuroImage, 50: 198-207, 2010.

Sugiura M, Wakusawa K, Sekiguchi A, Sassa Y, Jeong H, Horie K, Sato S, Kawashima R: Extraction of situational meaning by integrating multiple meanings in a complex environment: a functional MRI study. Human Brain Mapping. 30: 2678-2688, 2009.

Masunaga H, Kawashima R, Horn JL, Sassa Y, Sekiguchi A: Neural substrates of the topology test to measure fluid reasoning: An fMRI study. Intelligence. 36: 607-615, 2008.

Wan X, Sekiguchi A, Yokoyama S, Riera J, Kawashima R: Electromagnetic source imaging: Backus-Gilbert resolution spread function-constrained and functional MRI-guided spatial filtering. Human Brain Mapping. 29: 627-643, 2008.

【和文原著】

事崎由佳,竹内光,関口敦,山本悠貴,品田貴光,高橋慶,荒木剛,瀧靖之,荻野武,木口雅史,川島隆太:デイリー・ハッスルズに対するバイオフィードバック介入の効果.人工知能学会論文誌 571:1-4,2013.

服部朝美,関口敦,鹿野理子,金澤素,福土審:自律訓練法が奏功し行動範囲が拡大した全般性不安障害の1例.心療内科 12:402-406,2008.

間島富久子,岡山征史朗, 太田百合子, 川田まり,藤井康子,関口敦,苅部正巳,石川俊男:集団コラージュ療法が摂食障害入院患者に有用であったと考えられた1例.心身医学 47:123-131.2007.

山口利昌,関口敦,後藤直子,廣山夏生,苅部正巳,石川俊男:神経性食欲不振症の心理特性に関する検討.日本心療内科学会誌 9:3-10.2005.

山口利昌,関口敦,後藤直子,廣山夏生,苅部正巳,石川俊男:摂食異常症における身の治療的役割 神経性食欲不振症における身体的治療および入院治療の役割.日本心療内科学会誌 8:73-177.2004.

関口敦,安藤勝己,市岡陽子,野村幸伸,井村平治,貫名英之,判田正典,久保千春:不安障害を合併した過敏性腸症候群に絶食森田療法が奏効した1例.心療内科 7:504-509.2003.

関口敦,岩渕勝好,中嶋郁子,佐藤純香,有川卓,三井英明,折田博之,廣田茂樹,渡辺順之:学校検診で発見された多発性肺動静脈瘤の1若年例.山形市立病院済生館医学雑誌 27:120-125.2002.

【総説】

金吉晴,中島聡美,堀弘明,関口敦:不安障害、PTSDの治療と再燃に関わる要因.精神保健研究 62:35-39,2016.

関口敦:自尊心が守る脳と健康~東日本大震災における追跡調査から.Brain and Nerve,67(10):1193-1204,2015.

関口敦:震災直後に認められた脳形態変化の追跡調査-健常大学生における検討.心身医学,55(8):913-919,2015.

関口敦:PTSDにおける扁桃体.Clinical Neuroscience,32(6):686-689,2014.

Takeuchi H, Taki Y, Nouchi R, Hashizume H, Sekiguchi A, Kotozaki Y, Nakagawa S, Miyauchi CM, Sassa Y, Kawashima R: Effects of working memory-training on functional connectivity and cerebral blood flow during rest. Cortex Sep; 49(8): 2106-25, 2013.

Sekiguchi A, Sugiura M, Taki Y, Kotozaki Y, Nouchi R, Takeuchi H, Araki T, Hanawa S, Nakagawa S, Miyauchi CM, Sakuma a, Kawashima R: Causal Relationship Between Psychological Distress After a Severe Earthquake and Brain Structural Changes. Human Science & Technology, Vol. 10, 2012, 31-37, 2013.

関口敦,杉浦元亮, 事崎由佳,佐久間篤,瀧靖之,川島隆太:震災後精神症状の脆弱性・獲得因子の神経基盤の解明.トラウマティック・ストレス,vol.11-1,63-67,2013.

関口敦,川島隆太:認知リハビリテーション医学―認知症に対する学習療法.BRAIN and NERVE 59:357-365,2007.

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