Publication List 2007-2009

1. Oki, S, and S. Miyake: Invariant Natural Killer T (iNKT) cells in asthma: A novel insight into the pathogenesis of asthma and the therapeutic implication of glycolipid ligands for allergic diseases. Allergol Int 56:7-14, 2007
2. Kuroda, R, J-i. Satoh, T. Yamamura, T. Anezaki, T. Terada, K. Yamazaki, T. Obi, and K. Mizoguchi: A novel compound heterozygous mutation in the DAP12 gene in a patient with Nasu-Hakola disease. J Neurol Sci 252:88-91, 2007
3. Satoh, J-i, H. Tabunoki, T. Yamamura, K. Arima, and H. Konno: TROY and LINGO-1 expression in astrocytes and macrophages/microglia in MS brains. Neuropathol and Applied Neurobiol 33:99-107, 2007
4. Onoue, H, J-i. Satoh, M. Ogawa, and T. Yamamura : Detection of anti-Nogo receptor autoantibody in the serum of multiple sclerosis and controls. Acta Neurologica Scandin 115:153-160, 2007
5. Maresz, K, G. Pryce, E. D. Ponomarev, G. Marsicano, J. L. Croxford, L.P. Shriver, C. Ledent, X. Cheng, E. Carrier, M.K. Mann, G. Giovannoni, R. G. Pertwee, T. Yamamura, N.E. Buckley, C.J. Hillard, B. Lutz, D. Baker and B. N. Dittel: Direct Suppression of CNS Autoimmune inflammation via the cannabinoid receptor CB1 on neurons and CB2 on autoreactive T cells. Nat Med 13:492-497, 2007
6. Toba, T, K. Murata, K. Nakanishi, B. Takahashi, N. Takemoto, M. Akabane, T. Nakatsuka, S. Imajo, T. Yamamura, S. Miyake, and H. Annoura: Minimum structure requirement of immunomodulatory glycolipids for predominant Th2 cytokine induction and the discovery of non-linear phytosphingosine analogs. Bioorganic & Medicinal Chemistry Letters 17:278-2784, 2007
7. Miyake S, and T. Yamamura: Therapeutic potential of CD1d-restricted invariant natural killer T cell-based treatment for autoimmune diseases. Int Rev Immunol 26:73-94, 2007
8. Yamamura, T.: Interleukin 17-producing T-helper cells and autoimmune diseases: Time for a paradigm shift? Current Rheumatology Reports 9:93-95, 2007
9. Kaieda, S, S. Oki, C. Tomi, T. Yamamura and S. Miyake: Activation of invariant natural killer T cells by synthetic glycolipid ligands suppresses autoantibody-induced arthritis. Arthr Rheumat 56:1836-1845, 2007
10. Sato, W, T. Aranami, and T. Yamamura: Cutting Edge. Human Th17 cells are identified as bearing CCR2+CCR5-phenotype. J Immunol 178:7525-7529, 2007
11. Miyake, S. and T. Yamamura: NKT cells and autoimmune diseases: Unraveling the complexity. In T cell activation by CD1 and lipid antigens. (Edited by Branch D. Moody; Springer-Verlag), Current Topics in Microbiology and Immunology 314:251-265, 2007
12. Satoh, J-i, H. Tabunoki, T. Yamamura, K. Arima, and H. Konno: Human astrocytes express aquaporin-1 and aquaporin-4 in vitro and in vivo. Neuropathology 27: 245-256, 2007
13. Satoh, J, Z. Illes, A. Peterfalvi, H. Tabunoki, C. Rozsa, and T. Yamamura: Aberrant transcriptional regulatory network in T cells of multiple sclerosis. Neurosci Lett 422: 30-33, 2007
14. Sakuishi, K, S. Oki, M. Araki, S.A. Porcelli, S. Miyake, and T. Yamamura: Invariant NKT cells biased for IL-5 production act as crucial regulators of inflammation. J Immunol 179:3452-3462, 2007
15. Yamamura, T, K. Sakuishi, Zs. Illes, and S. Miyake: Understanding the behavior of invariant NKT cells in autoimmune diseases. J. Neuroimmunol. 191:8-15, 2007
16. Ambosino, E, M. Terabe, R.C. Halder, J. Peng, S. Takaku, S. Miyake, T. Yamamura, V. Kumar, and J.A. Berzofsky: Cross-regulation between type I and type II NKT cells in regulating tumor immunity: A new immunoregulatory axis. J Immunol 179:5126-5136, 2007
17. Sekine, C, T. Sugihara, S. Miyake, H. Hirai, M. Yoshida, N. Miyasaka, and H. Kohsaka. Successful treatment of animal models of rheumatoid arthritis with small-molecule cyclin-dependent kinase inhibitors. J Immunol 180:1954-1961, 2008
18. Croxford, J.L, G. Pryce, S.M. Jackson, C. Ledent, G. Giovannoni, R.G. Pertwee, T. Yamamura, and D. Baker: Cannabinoid-mediated neuroprotection, not immunosuppression, may be more relevant to multiple sclerosis. J Neuroimmunol 193: 120-129, 2008
19. Dondji, B, E. Deak, K. Goldsmith-Pestana, E. Perez-Jimenez, M. Esteban, S. Miyake, T. Yamamura and D. McMahon-Pratt. Intradermal activation of NKTi cells during DNA priming in heterologous prime-boost vaccination enhances effector and memory T cell responses and protection against Leishmania major infection. Eur J Immunol 38:706-719, 2008
20. Satoh, J-i, S. Obayashi, T. Misawa, H. Tabunoki, T. Yamamura, K. Arima, and H. Konno: Neuromyelitis optica/Devic's disease: Gene expression profiling of brain lesions. Neuropathology 28: 561-576, 2008
21. Aranami, T. and T. Yamamura: Th17 cells and autoimmune encephalomyelitis (EAE/MS). Allergol. Int. 57 115-120, 2008
22. Doi, Y, S. Oki, T. Ozawa, H. Hohjoh, S. Miyake, and T. Yamamura: Orphan nuclear receptor NR4A2 expressed in T cells from multiple sclerosis mediates production of inflammatory cytokines. Proc Natl Acad Sci U S A 105: 8381-8386, 2008
23. Okamoto, T, M. Ogawa, Y. Lin, M. Murata, S. Miyake, and T. Yamamura: Treatment of Neuromyelitis Optica: Current Debate. Therapeutic Advances in Neurological Disorders. 1: 43-52, 2008
24. IIjima, M, H. Koike, N. Hattori, A. Tamakoshi, M. Katsuno, F. Tanaka, M. Yamamoto, K. Aimura, G. Sobue and Refractory Peripheral Neuropathy Study Group of Japan (Including T. Yamamura). Prevalance and incidence rates of chronic inflammatory demyelinating polyneuropathy in the Japanese population. J Neurol Neurosurg Psychiatry 79: 1040-1043, 2008
25. Satoh, J-i, T. Misawa, H. Tabunoki, and T. Yamamura: Molecular network analysis of T-cell transcriptome suggests aberrant regulation of gene expression by NF-κB as a biomarker for relapse of multiple sclerosis. Dis Markers 25: 27-35, 2008
26. Shimamura, M, Y-Y. Huang, R. Migishima, M. Yokoyama, T. Saitoh, and T. Yamamura: Localization of NK1.1+ invariant Vα19 TCR+ cells in the liver with potential to promptly respond to TCR stimulation. Immunol Lett 121: 38-44, 2008
27. Araki, M, S. Miyake, and T. Yamamura: Synthetic glycolipid ligands for human iNKT cells as potential therapeutic agents for immunotherapy. Curr Medicinal Chem 15: 2337-2345, 2008
28. Yokote, H, S. Miyake, J.L. Croxford, S. Oki, H. Mizusawa, and T. Yamamura: NKT cell-dependent amelioration of a mouse model of multiple sclerosis by altering gut flora. Am J Pathol 173: 1714-1723, 2008
29. Osoegawa, M, J. Kira, T. Fukazawa, K. Fujihara, S. Kikuchi, M. Matsui, T. Kohriyama, G. Sobue, T. Yamamura, Y. Itoyama, T. Saida, K. Sakata, H. Ochi, and T. Matsuoka: The research Committee of Neuroimmunologic Diseases. Temporal changes and geographical differences in multiple sclerosis phenotypes in Japanese: nationwide survey results over 30 years. Mult Scler 15:159-173, 2009
30. Ishizu, T, JI. Kira, M. Osoegawa, T. Fukazawa, S. Kikuchi, K. Fujihara, M. Matsui, T. Kohriyama, G. Sobue, T. Yamamura, Itoyama Y, Saida T, Sakata K; The Research Committee of Neuroimmunological Diseases: Heterogeneity and continuum of multiple sclerosis phenotypes in Japanese according to the results of the fourth nationwide survey. J Neurol Sci 80:22-28, 2009
31. Satoh, J.I, H. Tabunoki, and T. Yamamura: Molecular network of the comprehensive multiple sclerosis brain lesion proteome. Mult Scler 15:531-541, 2009
32. Klemann, C, B.J.E. Raveney, A.K. Klemann, T. Ozawa, S. von Hoersten, K. Shudo, S. Oki and T. Yamamura: Synthetic retinoid AM80 inhibits Th17 cells and ameliorates EAE. Am J Pathol 174: 2234-2245, 2009
33. Croxford, J.L, and T. Yamamura: Back to the future for multiple sclerosis therapy: Focus on current and emerging disease-modifying therapeutic strategies. Immunotherapy 1: 403-424, 2009
34. Theil, M.M, S. Miyake, M. Mizuno, C. Tomi, J.L. Croxford, H. Hosoda, J. Theil, S. von Hoersten, H. Yokote, A. Chiba, Y. Lin, S. Oki, T. Akamizu, K. Kangawa, and T. Yamamura: Suppression of experimental autoimmune encephalomyelitis by Ghrelin. J Immunol 183: 2859-2866, 2009
35. Fujita, M, T. Otsuka, M. Mizuno, C. Tomi, T.M. Gallagher, T. Yamamura, and S. Miyake: Carcinoembryonic antigen-related cell adhesion molecule 1 modulates experimental autoimmune encephalomyelitis via iNKT cell-dependent mechanism. Am J Pathol 175: 1163-1123, 2009
36. Miyake, S, and T. Yamamura: Ghrelin: friend of foe for neuroinflammation. Discov Med 8: 64-67, 2009

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