Staff introduction
Sayuri Ishiwata
Section Chief, Section of Cognitive Function Research
Research and Biography
During my doctoral studies in the Ph.D. Program in Medical Sciences at Tokyo Medical and Dental University (now Institute of Science Tokyo), I investigated the molecular mechanisms and pathological roles of the brain D-serine system, focusing particularly on its involvement in schizophrenia and its potential as a therapeutic target.
At the Department of Mental Disorder Research, National Center of Neurology and Psychiatry, I analyzed D-serine and related biomarkers in cerebrospinal fluid and plasma samples from patients with psychiatric disorders. In parallel, through clinical experience as a hospital pharmacist, I developed a practical understanding of psychiatric pharmacotherapy and conducted clinical research aimed at identifying novel biomarkers for psychiatric disorders.
After moving to the United States, I trained in basic neuroscience research at the Laboratory of Molecular and Cellular Neurobiology at the National Institutes of Mental Health.
I am currently working at the National Center of Neurology and Psychiatry, where I conduct research on the role of inflammation and NMDA receptors in the pathophysiology of PTSD, integrating both basic and clinical approaches. My goal is to contribute to a deeper understanding of psychiatric disorders and to the development of more personalized, effective treatments.