2025
- Minakawa E, Owari K, Nogami N, Nakatani T, Koizumi M, Kawanobe A, Saga Y, Kudo M, Noguchi S, Hanakawa T, Hori Y, Numazawa H, Takeuchi T, Katakai Y, Saito R, Nagai Y, Saito Y, Tomioka I, Seki K: Establishment of a second-generation transgenic marmoset model with germline transmission that models polyglutamine disease. Disease Models & Mechanisms, 2025
- Philipp R, Hara Y, Uchida N, Ohta N, Oya T, Funato T, Seki K: Multi-timescale neural adaptation underlying long-term musculoskeletal reorganization. eLife, 2025
2024
- Kosugi A,Inoue K, Takada M, Seki K: Bidirectional Optogenetic Modulations of Peripheral Sensory Nerve Activity: Induction vs. Suppression through Channelrhodopsin and Halorhodopsin. iScience,2025
- Xiaoyu Guo, Subing Huang, Borong He, Chuanlin Lan, Jodie J Xie, Kelvin Y S Lau, Tomohiko Takei, Arthur D P Mak, Roy T H Cheung, Kazuhiko Seki, Vincent C K Cheung, Rosa H M Chan: Inhibitory Components in Muscle Synergies Factorized by the Rectified Latent Variable Model From Electromyographic Data. IEEE JOURNAL OF BIOMEDICAL AND HEALTH INFORMATICS.VOL.29,NO.2,Feb 2025
- Kubota S, Sasaki C, Kikuta S, Yoshida J, Ito S, Gomi H, Oya T, Seki K:Modulation of somatosensory signal transmission in the primate cuneate nucleus during voluntary hand movement. Cell Report 113884
2023
- Tomatsu S, Kim G, Kubota S, Seki K: Presynaptic gating of monkey proprioceptive signals for proper motor action. Nature Communications 14:6537. 2023
- Kohri N, Ohta M, Kousaku H, Minakawa EN, Seki K, Tomioka I: Optimization of piggyBac transposon-mediated gene transfer method in common marmoset embryos. Plos One. 2023
- Kosugi A, Saga Y, Kudo M, Koizumi M, Umeda T, Seki K: Time course of recovery of different motor functions following a reproducible cortical infarction in non-human primates. Front Neurol. 2023; 14: 1094774
2021
- 関和彦, 竹内雄一: 超音波ニューロモデュレーション. 中外医学社 Clinical Neuroscience 40巻2号 pp. 249-253
- Saito T, Ogihara N, Takei T, Seki K: Musculoskeletal modeling and inverse dynamic analysis of precision grip in the Japanese macaque. Front. Syst. Neurosci.,10 Dec 2021
- Kudo M, Wupuer S, Kubota S, Seki K: Distribution of Large and Small Dorsal Root Ganglion Neurons in Common Marmosets.Front. Syst. Neurosci., 02 Dec 2021
- Kudo M, Wupuer S, Fujiwara M, Saito Y, Kubota S, Inoue K, , Takada M, Seki K: Specific gene expression in unmyelinated dorsal root ganglion neurons in nonhuman primates by intra-nerve injection of adeno-associated virus 6 vector. Molecular Therapy : Methods and Clinical Development, 6 Aug 2021
- Koizumi M, Nogami N, Owari K, Kawanobe A, Nakatani T and Seki K : Motility Profile of Captive-Bred Marmosets Revealed by a Long-Term In-Cage Monitoring System. Front. Syst. Neurosci. 15:645308, 15 April 2021
- Cheung VCK, Seki K : Approaches to Revealing the Neural Basis of Muscle Synergies: A Review and A Critique. Journal of Neurophysiology, 17 March 2021
2020
- Yaron A, Kowalski D, Yaguchi H Takei T, Seki K : Forelimb force direction and magnitude independently controlled by spinal modules in the macaque. PNAS 117(44): 27655 - 27666, 15 October 2020
- Tomioka I, Nagai Y, Seki K : Generation of common marmoset model lines of spinocerebellar ataxia type 3. Front. Neurosci. doi: 10.3389/fnins.2020.548002
- Omata D, Hagiwara F, Munakata L, Shima T, Kageyama S, Suzuki Y, Azuma T, Takagi S, Seki K, Maruyama K, Suzuki R：Characterization of Brain-targeted Drug Delivery Enhanced by a Combination of Lipid-based Microbubbles and Non-focused Ultrasound. Journal of Pharmaceutical Sciences109（9)：2827−2835
- Oya T, Takei T, Seki K: Distinct sensorimotor feedback loops for dynamic and static control of primate precision grip. Communications Biology 3(156), 2020
2019
- Umeda T, Koizumi M, Katakai Y, Saito R, Seki K: Decoding of muscle activity from the sensorimotor cortex in freely behaving monkeys. NeuroImage 197: 512-526, 15 August 2019
- Umeda T, Isa T, Nishimura Y: The somatosensory cortex receives information about motor output, Science Advances, 5, eaaw5388, 2019
- Kubota S, Sidikejiang W, Kudo M, Inoue KI, Umeda T, Takada M, Seki K:Optogenetic recruitment of spinal reflex pathways from large-diameter primary afferents in non-transgenic rats transduced with AAV9/Channelrhodopsin 2. J Physiol, 2019
- Azim E, Seki K : Gain control in the sensorimotor system. Current Opinion in Physiology, March 2019
2018
- Kobayashi Y, Azuma T, Shimizu K, Koizumi M, Oya T, Suzuki R, Maruyama K, Seki K, Takagi S : Development of focus controlling method with tFUS aided by numerical simulation for non-invasive brain therapy, Jpn. J. Appl. Phys., accepted in Vol.57, No.7S1, June, 2018
- Tomioka I, Nagai Y, Seki K : Developing biomarkers for neurodegenerative diseases using genetically-modified common marmoset models. Neural Regen Res 13(7):1189-1190, July, 2018
2017
- Takei T, Confais J, Tomatsu S, Oya T, Seki K: Neural basis for hand muscle synergies in the primate spinal cord. Proc Natl Acad Sci 114 (32): 8643-8648, 2017
- Tomioka I, Nogami N, Nakatani T, Owari K, Fujita N, Motohashi H, Takayama O, Takae K, Nagai Y, Seki K：Generation of transgenic marmosets using a tetracyclin-inducible transgene expression system as a neurodegenerative disease model. Biol Reprod 97(5):772-780, 2017
- Kosugi A, Takemi M, Tia B, Castagnola E, Ansaldo A, Sato K, Awiszus F, Seki K, Ricci D, Fadiga L, Iriki A, Ushiba J: Accurate motor mapping in awake common marmosets using micro-electrocorticographical stimulation and stochastic threshold estimation. J Neural Eng 15(3):036019, 2018
2016
- Yamada H, Yaguchi H, Tomatsu S, Takei T, Oya T, Seki K: Representation of afferent signals from forearm muscle and cutaneous nerves in the primary somatosensory cortex of the macaque monkey. PLOS ONE 11 (10): e0163948-, 2016
- Matsuno H, Kudoh M, Watakabe A, Yamamori T, Shigemoto R, Nagao S: Distribution and Structure of Synapses on Medial Vestibular Nuclear Neurons Targeted by Cerebellar Flocculus Purkinje Cells and Vestibular Nerve in Mice: Light and Electron Microscopy Studies. PLOS ONE 11 (10): e0164037, 2016
- Tomatsu S, Kim G, Confais J, Seki K: Muscle afferent excitability testing in spinal root-intact rats: Dissociating peripheral afferent and efferent volleys generated by intraspinal microstimulation. J Neurophysiol 117(2):796-8007, Feb 2017
- Confais J, Kim G, Tomatsu S, Takei T, Seki K: Nerve-specific input modulation to spinal neurons during a motor task in the monkey. J Neurosci 37(10): 2612-2626, Mar 2017
- Tomioka I, Ishibashi H, Minakawa EN, Motohashi HH, Takayama O, Saito Y, Popiel AH, Puentes S, Owari K, Nakatani T, Nogami N, Yamamoto K, Noguchi S. Yonekawa T, Tanaka Y, Fujita N, Suzuki H, Kikuchi H, Aizawa S, Nagano S, Yamada D, Nishino I, Ichinohe N, Wada K, Kohsaka S, Nagai Y, Seki K: Transgenic monkey model of the polyglutamine diseases recapitulating progressive neurological symptoms. eNeuro. 4 (2) e 0250-16, 2017
- Tomatsu S, Ishikawa T, Tsunoda Y, Lee J, Hoffman D, Kakei S: Information processing in the hemisphere of the cerebellar cortex for control of wrist movement. J Neurophysiol 115(1):255-70, 2016
- Yaguchi H, Takei T, Kowalski D, Suzuki T, Mabuchi K, Seki K: Modulation of spinal motor output by initial arm postures in anesthetized Monkeys. J Neurosci 35(17): 6937-6945; doi: 10.1523/JNEUROSCI.3846-14. 2015
- Ishida A, Isa K, Umeda T, Kobayashi K, Kobayashi K, Hida H, Isa T: Causal Link between the Cortico-Rubral Pathway and Functional Recovery through Forced Impaired Limb Use in Rats with Stroke. J Neurosci 36(2):455 - 467, 2016
- Hirashima M, Oya T：How does the brain solve muscle redundancy? Filling the gap between optimization and muscle synergy hypotheses. Neurosci Res 104: 80-87, 2016
2014
- Umeda T, Watanabe H, Sato M, Kawato M, Isa T, Nishimura Y: Decoding of the spike timing of primary afferents during voluntary arm movements in monkeys. Front. Neuroscience, 8 : 97, 2014
- Puentes S, Kaido T, Hanakawa T, Ichinohe N, Otsuki T, Seki K: Internal capsule stroke in the common marmoset: Neuroscience 284 400-411, 2015
- 大屋知徹, 関和彦 : 中脳赤核と運動機能―系統発生的観点から― Red Nucleus and Its Motor Function –A Phylogenetic Perspective– Spinal Surgery 28(3): 258-263, 2014
- Umeda T, Isa T, Nishimura Y :Proprioceptive information coded by populational sensory afferents.
J. Phys. Fitness. Sports. Med.3: 477-482, 2014
2013
- Ishibashi H, Motohashi HH, Kumon M, Yamamoto K, Okada H, Okada T, Seki K: Efficient embryo transfer in the common marmoset monkey (Callithrix jacchus) with a reduced transfer volume: a non-surgical approach with cryo-preserved late-stage embryos.
Biology of Reproduction.88(5):115, 2013 May 9 - Okada H, Ishibashi H, Hayashita-Kinoh H, Chiyo T, Nitahara-Kasahara Y, Baba Y, Watanabe S, Takeda S, Okada T: Robust long-term transduction of common marmoset neuromuscular tissue with rAAV1 and rAAV9.
Molecular Therapy-Nucleic Acids 2:e95, 2013 May 28 - Hidetoshi Ishibashi, Hideyuki H. Motohashi, Mami Kumon, Kazuhiro Yamamoto,
Hironori Okada, Takashi Okada, Kazuhiko Seki: Ultrasound-guided non-surgical embryo collection in the common marmoset.
Reproductive Biology, Volume 13, Issue 2, June 2013, Pages 139-144 - Takei T, Seki K: Spinal premotor interneurons mediate dynamic and static motor commands for precision grip in monkeys.
The Journal of Neuroscience 33:8850-60, 2013 - Takei T, Seki K: Synaptic and functional linkages between spinal premotor interneurons and hand-muscle activity during precision grip.
Frontiers in Computational Neuroscience 7:40, 2013 - Yamada H, Inokawa H, Matsumoto N, Ueda Y, Enomoto K, Kimura M：Coding of the long-term value of multiple future rewards in the primate striatum. J Neurophysiol 109(4):1140-51, 2013
- Yamada H, Tymula A, Louie K, Glimcher PW.：Thirst-dependent risk preferences in monkeys identify a primitive form of wealth. Proc Natl Acad Sci U S A. 2013 Sept 24;110(39):15788-93.
- Ishibashi H, Motohashi HH: Artificial insemination in common marmosets using sperm
collected by penile vibratory stimulation. Neotropical Primates, 20 (1): 54-56, June 2013 - Ishibashi H, Motohashi HH, Kumon M, Yamamoto K, Okada H, Okada T, Seki K: Effect of the size of zona pellucida opening on hatching in the common marmoset monkey (Callithrix jacchus) embryo. Animal Science Journal 84(11):740-743. 2013
- Kumashiro M, Yokoyama O, Ishibashi H: Communicative pointing ameliorates grasping
deficits after an inactivation and lesions of the ventral premotor cortex in Japanese monkeys (Macaca fuscata). Journal of Neurological Disorders & Stroke 1(3): 1020, 2013 - Koshiba M, Senoo A, Mimura K, Shirakawa Y, Karino G, Obara S, Ozawa S, Sekihara H,
Fukushima Y, Ueda T, Kishino H, Tanaka T, Ishibashi H, Yamanouchi H, Yui K, Nakamura S:
A cross-species socio-emotional behaviour development revealed by a multivariate analysis.
Scientific Reports 3: 2630, 2013 - 戸松彩花 : 動きが思い通りだと知るために～exafferenceとreafferenceを弁別する2つのシステム～. バイオメカニクス研究 17 (3): 152-159, 2013
- Minamimoto T, Yamada H, Hori Y, Suhara T.：Hydration level is an internal variable for computing motivation to obtain water rewards in monkeys.Exp Brain Res. 2012 May;218(4):609-18.
2012
- Daisuke Yamada, Moeko Miyajima, Hidetoshi Ishibashi, Keiji Wada, Kazuhiko Seki, Masayuki Sekiguchi: Adult-like action potential properties and abundant GABAergic synaptic responses in amygdala neurons from newborn marmosets.The Journal of Physiology, 2012
- Umeda T, Seki K, Sato M, Nishimura Y, Kawato M, and Isa T: Population coding of forelimb joint kinematics by peripheral afferents in monkeys., PLoS One ,2012
- Seki, K. and Fetz, EE.: Gating of Sensory Input at Spinal and Cortical Levels during Preparation and Execution of Voluntary Movement. Journal of Neuroscience, 32(3): 890-902, Jan., 2012.
- 関和彦：「素顔のニューロサイエンティスト：Eberhard E Fetz」Clinical Neuroscience Vol. 30 (3)，2012
2011
- Matsuo T., Kawasaki K., Osada T., Sawahata H., Suzuki T., Shibata M., Miyakawa N,Nakahara K., Iijima A., Sato N., Kawai K., Saito N. &Hasegawa I.: Intrasulcal electrocorticography in macaque monkeys with minimally invasive neurosurgical protocols. Front. Syst. Neurosci. 5:34.doi:10.3389/fnsys.2011.00034.
- Jonas B Zimmermann., Seki K., Andrew Jackson.: Reanimating the arm and hand with intraspinal microstimulation. J. Neural Eng. 8(5). 054001, Aug, 2011
- Yamada H, Inokawa H, Matsumoto N, Ueda Y, Kimura M.: Neuronal basis for evaluating selected action in the primate striatum. Eur J Neurosci. Aug. 22., 2011
- Hideyuki H. Motohashi, Tadashi Sankai and Hidemi Kada.: Live offspring from cryopreserved embryos following in vitro growth, maturation and fertilization of oocytes derived from preantral follicles in mice. J. Reprod. Dev., 57, 715-722, 2011
- Koshiba M, Mimura K, Sugiura Y, Okuya T, Senoo A, Ishibashi H, Nakamura S：Reading marmoset behavior 'semantics' under particular social context by multi-parameters correlation analysis, Progress in Neuro-Psychopharmacology & Biological Psychiatry, 35: 1499-1504, 2011
2010
- Takei T, Seki K,: Spinal interneurons facilitate coactivation of hand muscles during a precision grip task in monkeys.The Journal of Neuroscience. 30:17041-50,2010.
- Seki K, Perlmutter S.I., Fetz E.E.: Task-dependent modulation of primary afferent depolarization in cervical spinal cord of monkeys performing an instructed delay task. J Neurophysiol 102: 85-99, 2009.
- Masamizu Y, Okada T, Ishibashi H, Takeda S, Yuasa S, Nakahara K: Efficient gene transfer into neurons in monkey brain by adeno-associated virus 8. Neuroreport 21: 447-451, 2010.
2009
- Koba R, Izumi A, Nakamura K: Sexual dimorphism in facial shapes and their discrimination, J Comp Psychol 123: 326-333, 2009.
- Tsuchida J, Izumi A: The effects of age and sex on interest toward movies of conspecifics in Japanese macaques (Macaca fuscata). J Am Assoc Lab Anim Sci 48: 286-291, 2009.
- Utama NP, Takemoto A, Koike Y, Nakamura K: Phased processing of facial emotion: An ERP study. Neurosci Res 64: 30-40, 2009.
- Yamaguchi C, Izumi A, Nakamura K: Temporal rules in vocal exchanges of phees and trills in common marmosets (Callithrix jacchus). Am J Primatol 71: 617-622, 2009.
- Motohashi HH, Sankai T, Nariai K, Sato K, Kada H: Effects of in vitro culture of mouse fetal gonads on subsequent ovarian development in vivo and oocyte maturation in vitro. Hum. Cell, 22: 43-48, 2009.
- Fukuoka T, Sumida K, Yamada T, Higuchi C, Nakagaki K, Nakamura K, Kohsaka S, Oeda K: Gene expression profiles in the common marmoset brain determined using a newly developed common marmoset-specific DNA microarray. Neurosci Res 66: 62-85, 2010.